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Leading the charge in leptin research: an interview with Jeffrey Friedman

Disease Models & Mechanisms · 2012

doi:10.1242/dmm.010629 (opens in a new tab)

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Abstract

Jeffrey Friedman is a molecular geneticist whose group, in 1994, reported the long-sought identity and function of leptin (Zhang et al., 1994), a key fat-derived hormone that regulates feeding behaviour and body weight. This represented a massive step forward in our understanding of obesity, which is now one of the world’s fastest-growing health problems. Here, he recalls his journey of discovery and offers his perspective on the future of obesity research.

Abstract licence: CC BY

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