2015 update of the evidence base: World Allergy Organization anaphylaxis guidelines

Abstract

The World Allergy Organization (WAO) Guidelines for the assessment and management of anaphylaxis provide a unique global perspective on this increasingly common, potentially life-threatening disease. Recommendations made in the original WAO Anaphylaxis Guidelines remain clinically valid and relevant, and are a widely accessed and frequently cited resource. In this 2015 update of the evidence supporting recommendations in the Guidelines, new information based on anaphylaxis publications from January 2014 through mid- 2015 is summarized. Advances in epidemiology, diagnosis, and management in healthcare and community settings are highlighted. Additionally, new information about patient factors that increase the risk of severe and/or fatal anaphylaxis and patient co-factors that amplify anaphylactic episodes is presented and new information about anaphylaxis triggers and confirmation of triggers to facilitate specific trigger avoidance and immunomodulation is reviewed. The update includes tables summarizing important advances in anaphylaxis research.

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     Basophil activation test discriminates between allergy and tolerance in peanut-sensitized children · 2014

     No notice
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     Muller UR, Ring J. When can immunotherapy for insect sting allergy be stopped? J Allergy Clin Immunol Pract. 2015;3:324-8.

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     Palgan K, Bartuzi Z, Gotz-Zbikowska M. Treatment with a combination of omalizumab and specific immunotherapy for severe anaphylaxis after a wasp sting. Int J Immunopathol Pharmacol. 2014;27:109-12.

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     Baker TW, Forester JP, Johnson ML, Stolfi A, Stahl MC. The HIT study: Hymenoptera Identification Test – how accurate are people at identifying stinging insects? Ann Allergy Asthma Immunol. 2014;113:267-70.

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     Park MA, Solensky R, Khan DA, Castells MC, Macy EM, Lang DM. Patients with positive skin test results to penicillin should not undergo penicillin or amoxicillin challenge. J Allergy Clin Immunol. 2015;135:816-7.

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     Hong DI, Dioun AF. Indications, protocols, and outcomes of drug desensitizations for chemotherapy and monoclonal antibodies in adults and children. J Allergy Clin Immunol Pract. 2014;2:13-9.

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     Kelso JM. Influenza vaccine and egg allergy: nearing the end of an evidence-based journey. J Allergy Clin Immunol Pract. 2015;3:140-1.

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Cited by papers we hold 5

• New Perspectives in Food Allergy · 2020
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• Global Trends in Anaphylaxis Epidemiology and Clinical Implications · 2020
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• Bee Updated: Current Knowledge on Bee Venom and Bee Envenoming Therapy · 2019
  No notice
• Endothelial Regulator of Calcineurin 1 Promotes Barrier Integrity and Modulates Histamine-Induced Barrier Dysfunction in Anaphylaxis · 2017
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• Update on perioperative hypersensitivity reactions: joint document from the Brazilian Society of Anesthesiology (SBA) and Brazilian Association of Allergy and Immunology (ASBAI) - Part II: etiology and diagnosis
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