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Acute kidney injury in major abdominal surgery: incidence, risk factors, pathogenesis and outcomes

Joana Gameiro, José Agapito Fonseca, Marta Neves and 2 more

Annals of Intensive Care · 2018 · Review · CC BY-NC-ND

doi:10.1186/s13613-018-0369-7

Abstract

Acute kidney injury (AKI) is a common complication in patients undergoing major abdominal surgery. Various recent studies using modern standardized classifications for AKI reported a variable incidence of AKI after major abdominal surgery ranging from 3 to 35%. Several patient-related, procedure-related factors and postoperative complications were identified as risk factors for AKI in this setting. AKI following major abdominal surgery has been shown to be associated with poor short- and long-term outcomes. Herein, we provide a contemporary and critical review of AKI after major abdominal surgery focusing on its incidence, risk factors, pathogeny and outcomes.

Shown for reading. Its publisher allows quoting it, not republishing it.

References 108

  1. 1.

    Chertow G, Burdick E, Honour M, Bonventre J, Bates D. Acute kidney injury, mortality, length of stay, and costs in hospitalized patients. J Am Soc Nephrol. 2005;16(11):3365-3370.

    Not in our library10.1681/asn.2004090740

  2. 2.

    Uchino S, Kellum JA, Bellomo R, et al. Beginning and Ending Supportive Therapy for the Kidney (BEST Kidney) Investigators. Acute renal failure in critically ill patients: a multinational, multicenter study. JAMA. 2005;294(7):813-818.

    Not in our library10.1001/jama.294.7.813

  3. 3.

    Barrantes F, Tian J, Vazquez R, Amoateng-Adjepong Y, Manthous CA. Acute kidney injury criteria predict outcomes of critically ill patients. Crit Care Med. 2008;36:1397-1403.

    Not in our library10.1097/ccm.0b013e318168fbe0

  4. 4.

    Cho E, Kim SC, Kim MG, Jo S-K, Cho W-Y, Kim H-K. The incidence and risk factors of acute kidney injury after hepatobiliary surgery: a prospective observational study. BMC Nephrol. 2014;15:169.

    Not in our library10.1186/1471-2369-15-169

  5. 5.

    Ryden L, Sartipy U, Evans M, Holzmann MJ. Acute kidney injury after coronary artery bypass grafting and long-term risk of end-stage renal disease. Circulation. 2014;130:2005-2011.

    Not in our library10.1161/circulationaha.114.010622

  6. 6.

    Elmistekawy E, McDonald B, Hudson C, et al. Clinical impact of mild acute kidney injury after cardiac surgery. Ann Thorac Surg. 2014;98:815-822.

    Not in our library10.1016/j.athoracsur.2014.05.008

  7. 7.

    Hobson C, Ozrazgat-Baslanti T, Kuxhausen A, et al. Cost and mortality associated with postoperative acute kidney injury. Ann Surg. 2015;261:1207-1214.

    Not in our library10.1097/sla.0000000000000732

  8. 8.

    Teixeira C, Rosa R, Rodrigues N, et al. Acute kidney injury after major abdominal surgery: a retrospective cohort analysis. Crit Care Res Pract. 2014;2014:132175.

    Not in our library10.1155/2014/132175

  9. 9.

    Vaught A, Ozrazgat-Baslanti T, Javed A, et al. Acute kidney injury in major gynaecological surgery: an observational study. BJOG. 2015;122:1340-1348.

    Not in our library10.1111/1471-0528.13026

  10. 10.

    Harris DG, Koo G, McCrone MP, et al. Acute kidney injury in critically ill vascular surgery patients is common and associated with increased mortality. Front Surg. 2015;2:8.

    Not in our library10.3389/fsurg.2015.00008

  11. 11.
    Determinants of postoperative acute kidney injury · 2009
    No notice
  12. 12.

    Biteker M, Dayan A, Tekkesin AI, et al. Incidence, risk factors, and outcomes of perioperative acute kidney injury in noncardiac and nonvascular surgery. Am J Surg. 2014;207:53-59.

    Not in our library10.1016/j.amjsurg.2013.04.006

  13. 13.

    Drews JD, Patel HJ, Williams DM, et al. The impact of acute renal failure on early and late outcomes after thoracic aortic endovascular repair. Ann Thorac Surg. 2014;97:2027-2033.

    Not in our library10.1016/j.athoracsur.2014.02.045

  14. 14.

    Kandler K, Jensen ME, Nilsson JC, et al. Acute kidney injury is independently associated with higher mortality after cardiac surgery. J Cardiothorac Vasc Anesth. 2014;28:1448-1452.

    Not in our library10.1053/j.jvca.2014.04.019

  15. 15.

    Munoz-Garcia AJ, Munoz-Garcia E, Jimenez-Navarro MF, et al. Clinical impact of acute kidney injury on short- and long-term outcomes after transcatheter aortic valve implantation with the CoreValve prosthesis. J Cardiol. 2015;66:46-49.

    Not in our library10.1016/j.jjcc.2014.09.009

  16. 16.

    Zhu JC, Chen SL, Jin GZ, et al. Acute renal injury after thoracic endovascular aortic repair of Stanford type B aortic dissection: incidence, risk factors, and prognosis. J Formos Med Assoc. 2014;113:612-619.

    Not in our library10.1016/j.jfma.2014.01.017

  17. 17.

    Pickering JW, James MT, Palmer SC. Acute kidney injury and prognosis after cardiopulmonary bypass: a meta-analysis of cohort studies. Am J Kidney Dis. 2015;65:283-293.

    Not in our library10.1053/j.ajkd.2014.09.008

  18. 18.

    Adalbert S, Adelina M, Romulus T, et al. Acute kidney injury in peripheral arterial surgery patients: a cohort study. Ren Fail. 2013;35:1236-1239.

    Not in our library10.3109/0886022x.2013.823830

  19. 19.

    Kheterpal S, Tremper KK, Englesbe MJ, et al. Predictors of post-operative acute renal failure after noncardiac surgery in patients with previously normal renal function. Anesthesiology. 2007;107:892-902.

    Not in our library10.1097/01.anes.0000290588.29668.38

  20. 20.

    Bihorac A, Yavas S, Subbiah S, et al. Long-term risk of mortality and acute kidney injury during hospitalization after major surgery. Ann Surg. 2009;249:851-858.

    Not in our library10.1097/sla.0b013e3181a40a0b

  21. 21.

    Hobson CE, Yavas S, Segal MS, et al. Acute kidney injury is associated with increased long-term mortality after cardiothoracic surgery. Circulation. 2009;119:2444-2453.

    Not in our library10.1161/circulationaha.108.800011

  22. 22.

    Hansen MK, Gammelager H, Mikkelsen MM, et al. Postoperative acute kidney injury and five-year risk of death, myocardial infarction, and stroke among elective cardiac surgical patients: a cohort study. Crit Care. 2013;17:R292.

    Not in our library10.1186/cc13158

  23. 23.

    O’Connor M, Kirwan C, Pearse R, Prowle JR. Incidence and associations of acute kidney injury after major abdominal surgery. Intensive Care Med. 2016;42(4):521-530.

    Not in our library10.1007/s00134-015-4157-7

  24. 24.

    Sirvinskas E, Andrejaitiene J, Raliene L, et al. Cardiopulmonary bypass management and acute renal failure: risk factors and prognosis. Perfusion. 2008;23(6):323-327.

    Not in our library10.1177/0267659109105251

  25. 25.

    De Santo LS, Romano G, Galdieri N, et al. RIFLE criteria for acute kidney injury in valvular surgery. J Heart Valve Dis. 2010;19(1):139-147.

    Not in our library

  26. 26.

    Svensson L, Crawford E, Hess K, Coselli J, Safi H. Experience with 1509 patients undergoing thoracoabdominal aortic operations. J Vasc Surg. 1993;17(2):357-368.

    Not in our library10.1016/0741-5214(93)90421-h

  27. 27.

    Svensson L, Coselli J, Safi H, Hess K, Crawford E. Appraisal of adjuncts to prevent acute renal failure after surgery on the thoracic or thoracoabdominal aorta. J Vasc Surg. 1989;10(3):230-239.

    Not in our library10.1016/0741-5214(89)90435-7

  28. 28.

    Wald R, Waikar S, Liangos O, Pereira B, Chertow G, Jaber B. Acute renal failure after endovascular vs open repair of abdominal aortic aneurysm. J Vasc Surg. 2006;43(3):460-466.

    Not in our library10.1016/j.jvs.2005.11.053

  29. 29.

    Tallgren M, Niemi T, Pöyhiä R, et al. Acute renal injury and dysfunction following elective abdominal aortic surgery. Eur J Vasc Endovasc Surg. 2007;33(5):550-555.

    Not in our library10.1016/j.ejvs.2006.12.005

  30. 30.

    Arnaoutakis G, Bihorac A, Martin T, et al. RIFLE criteria for acute kidney injury in aortic arch surgery. J Thorac Cardiovasc Surg. 2007;134(6):1554-1560.

    Not in our library10.1016/j.jtcvs.2007.08.039

  31. 31.

    Mori Y, Sato N, Kobayashi Y, Ochiai R. Acute kidney injury during aortic arch surgery under deep hypothermic circulatory arrest. J Anesth. 2011;25(6):799-804.

    Not in our library10.1007/s00540-011-1210-8

  32. 32.

    Causey M, Maykel J, Hatch Q, Miller S, Steele S. Identifying risk factors for renal failure and myocardial infarction following colorectal surgery. J Surg Res. 2011;170(1):32-37.

    Not in our library10.1016/j.jss.2011.03.027

  33. 33.

    Cho A, Lee J, Kwon G, et al. Post-operative acute kidney injury in patients with renal cell carcinoma is a potent risk factor for new-onset chronic kidney disease after radical nephrectomy. Nephrol Dial Transplant. 2011;26(11):3496-3501.

    Not in our library10.1093/ndt/gfr094

  34. 34.
    Epidemiology of AKI: Utilizing Large Databases to Determine the Burden of AKI · 2017
    No notice
  35. 35.
    Acute renal failure – definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group · 2004
    No notice
  36. 36.
    Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury · 2007
    No notice
  37. 37.

    Kidney Disease: Improving Global Outcomes (KDIGO) Acute Kidney Injury Work Group. KDIGO clinical practice guideline for acute kidney injury. Kidney Int Suppl. 2012;2:S1-S138.

    Not in our library10.1038/kisup.2012.1

  38. 38.

    Kellum JA, Lameire N, KDIGO AKI Guideline Work Group. Diagnosis, evaluation, and management of acute kidney injury: a KDIGO summary (Part 1). Crit Care. 2013;17(1):204.

    Not in our library10.1186/cc11454

  39. 39.

    Lameire N, Van Biesen W, Vanholder R. The changing epidemiology of acute renal failure. Nat Clin Nephrol. 2006;2:364-377.

    Not in our library10.1038/ncpneph0218

  40. 40.

    Brown J, Rezaee M, Marshall E, Matheny M. Hospital mortality in the United States following acute kidney injury. Biomed Res Int. 2016;2016:4278579.

    Not in our library10.1155/2016/4278579

  41. 41.

    Ympa YP, Sakr Y, Reinhart K, Vincent JL. Has mortality from acute renal failure decreased? A systematic review of the literature. Am J Med. 2005;118:827-832.

    Not in our library10.1016/j.amjmed.2005.01.069

  42. 42.

    Liaño F, Junco E, Pascual J, Madero R, Verde E. The spectrum of acute renal failure in the intensive care unit compared with that seen in other settings. The Madrid Acute Renal Failure Study Group. Kidney Int Suppl. 1998;66:S16-S24.

    Not in our library

  43. 43.

    Bellomo R. The epidemiology of acute renal failure: 1975 versus 2005. Curr Opin Crit Care. 2006;12:557-560.

    Not in our library10.1097/01.ccx.0000247443.86628.68

  44. 44.

    Thakar CV, Christianson A, Freyberg R, Almenoff P, Render ML. Incidence and outcomes of acute kidney injury in intensive care units: a Veterans Administration study. Crit Care Med. 2009;37(9):2552-2558.

    Not in our library10.1097/ccm.0b013e3181a5906f

  45. 45.
    Epidemiology of Acute Kidney Injury in the Intensive Care Unit · 2013
    No notice
  46. 46.
    RIFLE criteria for acute kidney injury are associated with hospital mortality in critically ill patients: a cohort analysis · 2006
    No notice
  47. 47.

    Thakar CV. Perioperative acute kidney injury. Adv Chronic Kidney Dis. 2013;20:67-75.

    Not in our library10.1053/j.ackd.2012.10.003

  48. 48.

    Grams ME, Sang Y, Coresh J, et al. Acute kidney injury after major surgery: a retrospective analysis of veteran’s health administration data. Am J Kidney Dis. 2016;67(6):872-880.

    Not in our library10.1053/j.ajkd.2015.07.022

  49. 49.

    Macedo E. Urine output assessment as a clinical quality measure. Nephron. 2015;131:252-254.

    Not in our library10.1159/000437312

  50. 50.

    Macedo E, Malhotra R, Bouchard J, Wynn S, Mehta R. Oliguria is an early predictor of higher mortality in critically ill patients. Kidney Int. 2011;80(7):760-767.

    Not in our library10.1038/ki.2011.150

  51. 51.

    Alpert RA, Roizen MF, Hamilton WK, et al. Intraoperative urinary output does not predict postoperative renal function in patients undergoing abdominal aortic revascularization. Surgery. 1984;95:707-711.

    Not in our library

  52. 52.

    Hahn RG. Volume kinetics for infusion fluids. Anesthesiology. 2010;113(2):470-481.

    Not in our library10.1097/aln.0b013e3181dcd88f

  53. 53.

    Goren O, Matot I. Perioperative acute kidney injury. Br J Anaesth. 2015;115(Suppl 2):ii3-ii14.

    Not in our library10.1093/bja/aev380

  54. 54.

    Koyner JL, Parikh CR. Clinical utility of biomarkers of AKI in cardiac surgery and critical illness. Clin J Am Soc Nephrol. 2013;8(6):1034-1042.

    Not in our library10.2215/cjn.05150512

  55. 55.

    Han WK, Wagener G, Zhu Y, Wang S, Lee HT. Urinary biomarkers in the early detection of acute kidney injury after cardiac surgery. Clin J Am Soc Nephrol. 2009;4(5):873-882.

    Not in our library10.2215/cjn.04810908

  56. 56.
    Urinary TIMP-2 and IGFBP7 as Early Biomarkers of Acute Kidney Injury and Renal Recovery following Cardiac Surgery · 2014
    No notice
  57. 57.

    Calvert S, Shaw A. Perioperative acute kidney injury. Perioper Med. 2012;4(1):6.

    Not in our library10.1186/2047-0525-1-6

  58. 58.

    Bell S, Davey P, Nathwani D, et al. Risk of AKI with gentamicin as surgical prophylaxis. J Am Soc Nephrol. 2014;25(11):2625-2632.

    Not in our library10.1681/asn.2014010035

  59. 59.

    Armstrong T, Welsh FK, Wells J, Chandrakumaran K, John TG, Rees M. The impact of pre-operative serum creatinine on short-term outcomes after liver resection. HPB (Oxford). 2009;11:622-628.

    Not in our library10.1111/j.1477-2574.2009.00094.x

  60. 60.

    Correa-Gallego C, Berman A, Denis SC, et al. Renal function after low central venous pressure-assisted liver resection: assessment of 2116 cases. HPB (Oxford). 2015;17:258-264.

    Not in our library10.1111/hpb.12347

  61. 61.

    Causey MW, Maykel JA, Hatch Q, Miller S, Steele SR. Identifying risk factors for renal failure and myocardial infarction following colorectal surgery. J Surg Res. 2011;170:32-37.

    Not in our library10.1016/j.jss.2011.03.027

  62. 62.

    Lee EH, Kim HR, Baek SH, et al. Risk factors of postoperative acute kidney injury in patients undergoing esophageal cancer surgery. J Cardiothorac Vasc Anesth. 2014;28:948-954.

    Not in our library10.1053/j.jvca.2013.12.006

  63. 63.

    Bredt L, Peres L. Risk factors for acute kidney injury after partial hepatectomy. World J Hepatol. 2017;9(18):815-822.

    Not in our library10.4254/wjh.v9.i18.815

  64. 64.

    Slankamenac K, Breitenstein S, Held U, Beck-Schimmer B, Puhan MA, Clavien PA. Development and validation of a prediction score for postoperative acute renal failure following liver resection. Ann Surg. 2009;250:720-728.

    Not in our library10.1097/sla.0b013e3181bdd840

  65. 65.

    Tomozawa A, Ishikawa S, Shiota N, Cholvisudhi P, Makita K. Perioperative risk factors for acute kidney injury after liver resection surgery: an historical cohort study. Can J Anaesth. 2015;62:753-761.

    Not in our library10.1007/s12630-015-0397-9

  66. 66.

    Ford MK, Beattie SW, Wijeysundera DN. systematic review: prediction of perioperative cardiac complications and mortality by the revised cardiac risk index. Ann Intern Med. 2010;152:26-35.

    Not in our library10.7326/0003-4819-152-1-201001050-00007

  67. 67.

    Kambakamba P, Slankamenac K, Tschuor C, et al. Epidural analgesia and perioperative kidney function after major liver resection. Br J Surg. 2015;102:805-812.

    Not in our library10.1002/bjs.9810

  68. 68.

    Kim CS, Oak CY, Kim HY, et al. Incidence, predictive factors, and clinical outcomes of acute kidney injury after gastric surgery for gastric cancer. PLoS ONE. 2013;8:e82289.

    Not in our library10.1371/journal.pone.0082289

  69. 69.

    Sun LY, Wijeysundera DN, Tait GA, Beattie WS. Association of intraoperative hypotension with acute kidney injury after elective noncardiac surgery. Anesthesiology. 2015;123:515-523.

    Not in our library10.1097/aln.0000000000000765

  70. 70.

    de Haan JE, Hoorn EJ, de Geus HRH. Acute kidney injury after liver transplantation: recent insights and future perspectives. Best Pract Res Clin Gastroenterol. 2017;31(2):161-169.

    Not in our library10.1016/j.bpg.2017.03.004

  71. 71.

    Chen J, Singhapricha T, Hu K-Q, et al. Postliver transplant acute renal injury and failure by the RIFLE criteria in patients with normal pretransplant serum creatinine concentrations: a matched study. Transplantation. 2011;91:348-353.

    Not in our library10.1097/tp.0b013e31820437da

  72. 72.

    Thakar CV, Kharat V, Blanck S, Leonard AC. Acute kidney injury after gastric bypass surgery. Clin J Am Soc Nephrol. 2007;2(3):426-430.

    Not in our library10.2215/cjn.03961106

  73. 73.

    Weingarten TN, Gurrieri C, McCaffrey JM, et al. Acute kidney injury following bariatric surgery. Obes Surg. 2013;23(1):64-70.

    Not in our library10.1007/s11695-012-0766-1

  74. 74.

    Almac E, Ince C. The impact of storage on red cell function in blood transfusion. Best Pract Res Clin Anaesthesiol. 2007;21(2):195-208.

    Not in our library10.1016/j.bpa.2007.01.004

  75. 75.

    Koch C, Li L, Sessler D, et al. Duration of red-cell storage and complications after cardiac surgery. N Engl J Med. 2008;358(12):1229-1239.

    Not in our library10.1056/nejmoa070403

  76. 76.

    Karkouti K, Wijeysundera D, Yau TM, et al. Acute kidney injury after cardiac surgery. Focus on modifiable risk factors. Circulation. 2009;119(4):495-502.

    Not in our library10.1161/circulationaha.108.786913

  77. 77.

    Ricci Z, Romagnoli S, Ronco C. Perioperative intravascular volume replacement and kidney insufficiency. Best Pract Res Clin Anaesthesiol. 2012;26(4):463-474.

    Not in our library10.1016/j.bpa.2012.11.001

  78. 78.

    Myburgh JA, Finfer S, Bellomo R, et al. Hydroxyethyl starch or saline for fluid resuscitation in intensive care. N Engl J Med. 2012;367:1901-1911.

    Not in our library10.1056/nejmoa1209759

  79. 79.

    Perel P, Roberts I, Ker K. Colloids versus crystalloids for fluid resuscitation in critically ill patients. Cochrane Database Syst Rev. 2013;2:CD000567.

    Not in our library10.1002/14651858.cd000567.pub6

  80. 80.

    Raiman M, Mitchell C, Biccard B, Rodseth R. Comparison of hydroxyethyl starch colloids with crystalloids for surgical patients: a systematic review and meta-analysis. Eur J Anaesthesiol. 2016;33(1):42-48.

    Not in our library10.1097/eja.0000000000000328

  81. 81.

    Zazzeron L, Gattinoni L, Caironi P, et al. Role of albumin, starches and gelatins versus crystalloids in volume resuscitation of critically ill patients. Curr Opin Crit Care. 2016;22(5):428-436.

    Not in our library10.1097/mcc.0000000000000341

  82. 82.

    Shaw AD, Kellum JA. The risk of AKI in patients treated with intravenous solutions containing hydroxyethyl starch. Clin J Am Soc Nephrol. 2013;8(3):497-503.

    Not in our library10.2215/cjn.10921012

  83. 83.

    Kim SK, Choi SS, Sim JH, et al. Effect of hydroxyethyl starch on acute kidney injury after living donor hepatectomy. Transplant Proc. 2016;48(1):102-106.

    Not in our library10.1016/j.transproceed.2015.12.016

  84. 84.

    Vives M, Callejas R, Duque P, et al. Modern hydroxyethyl starch and acute kidney injury after cardiac surgery: a prospective multicentre cohort. Br J Anaesth. 2016;117(4):458-463.

    Not in our library10.1093/bja/aew258

  85. 85.

    Umegaki T, Uba T, Sumi C, et al. Impact of hydroxyethyl starch 70/0.5 on acute kidney injury after gastroenterological surgery. Korean J Anesthesiol. 2016;69(5):460-467.

    Not in our library10.4097/kjae.2016.69.5.460

  86. 86.

    Sear J. Kidney dysfunction in the postoperative period. Br J Anaesth. 2005;95(1):20-32.

    Not in our library10.1093/bja/aei018

  87. 87.

    Carmichael P, Carmichael AR. Acute renal failure in the surgical setting. ANZ J Surg. 2003;73:144-153.

    Not in our library10.1046/j.1445-2197.2003.02640.x

  88. 88.

    Levy EM, Viscoli CM, Horwitz RI. The effect of acute renal failure on mortality. A cohort analysis. JAMA. 1996;275:1489-1494.

    Not in our library10.1001/jama.1996.03530430033035

  89. 89.

    Grams ME, Rabb H. The distant organ effects of acute kidney injury. Kidney Int. 2012;81:942-948.

    Not in our library10.1038/ki.2011.241

  90. 90.

    Kerrigan CL, Stotland MA. Ischemia reperfusion injury: a review. Microsurgery. 1993;14:165-175.

    Not in our library10.1002/micr.1920140307

  91. 91.

    Welborn MB, Oldenburg HS, Hess PJ, et al. The relationship between visceral ischemia, proinflammatory cytokines, and organ injury in patients undergoing thoracoabdominal aortic aneurysm repair. Crit Care Med. 2000;28:3191-3197.

    Not in our library10.1097/00003246-200009000-00013

  92. 92.

    Gobe G, Willgoss D, Hogg N, Schoch E, Endre Z. Cell survival or death in renal tubular epithelium after ischemia- reperfusion injury. Kidney Int. 1999;56:1299-1304.

    Not in our library10.1046/j.1523-1755.1999.00701.x

  93. 93.

    Neves JB, Jorge S, Lopes JA. Acute kidney injury: epidemiology, diagnosis, prognosis, and future directions. EMJ Nephrol. 2015;3(1):90-96.

    Not in our library

  94. 94.

    Chertow GM, Burdick E, Honour M, Bonventre JV, Bates DW. Acute kidney injury, mortality, length of stay, and costs in hospitalized patients. J Am Soc Nephrol. 2005;16:3365-3370.

    Not in our library10.1681/asn.2004090740

  95. 95.
    Acute kidney injury in intensive care unit patients: a comparison between the RIFLE and the Acute Kidney Injury Network classifications · 2008
    No notice
  96. 96.

    Ostermann M, Chang RW. Acute kidney injury in the intensive care unit according to RIFLE. Crit Care Med. 2007;35:1837-1843.

    Not in our library10.1097/01.ccm.0000277041.13090.0a

  97. 97.

    Lai CF, Wu VC, Huang TM, et al. Kidney function decline after a non-dialysis-requiring acute kidney injury is associated with higher long-term mortality in critically ill survivors. Crit Care. 2012;16:R123.

    Not in our library10.1186/cc11419

  98. 98.

    Coca SG, Peixoto AJ, Garg AX, Krumholz HM, Parikh CR. The prognostic importance of a small acute decrement in kidney function in hospitalized patients: a systematic review and meta-analysis. Am J Kidney Dis. 2007;50(5):712-720.

    Not in our library10.1053/j.ajkd.2007.07.018

  99. 99.

    Li X, Hassoun HT, Santora R, Rabb H. Organ crosstalk: the role of the kidney. Curr Opin Crit Care. 2009;15:481-487.

    Not in our library10.1097/mcc.0b013e328332f69e

  100. 100.

    Coca SG, Yusuf B, Shlipak MG, Garg AX, Parikh CR. Long-term risk of mortality and other adverse outcomes after acute kidney injury: a systematic review and meta-analysis. Am J Kidney Dis. 2009;53:961-973.

    Not in our library10.1053/j.ajkd.2008.11.034

  101. 101.

    Linder A, Fjell C, Levin A, Walley KR, Russell JA, Boyd JH. Small acute increases in serum creatinine are associated with decreased long-term survival in the critically ill. Am J Respir Crit Care Med. 2014;189(9):1075-1081.

    Not in our library10.1164/rccm.201311-2097oc

  102. 102.

    Ferenbach DA, Bonventre JV. Mechanisms of maladaptive repair after AKI leading to accelerated kidney ageing and CKD. Nat Rev Nephrol. 2015;11(5):264-276.

    Not in our library10.1038/nrneph.2015.3

  103. 103.

    Coca SG, Singanamala S, Parikh CR. Chronic kidney disease after acute kidney injury: a systematic review and meta-analysis. Kidney Int. 2012;81:442-448.

    Not in our library10.1038/ki.2011.379

  104. 104.

    Spurgeon-Pechman KR, Donohoe DL, Mattson DL, Lund H, James L, Basile DP. Recovery from acute renal failure predisposes hypertension and secondary renal disease in response to elevated sodium. Am J Physiol Renal Physiol. 2007;293:F269-F278.

    Not in our library10.1152/ajprenal.00279.2006

  105. 105.

    Basile DP. The endothelial cell in ischemic acute kidney injury: implications for acute and chronic function. Kidney Int. 2007;72:151-156.

    Not in our library10.1038/sj.ki.5002312

  106. 106.

    Sarafidis PA, Bakris GL. Microalbuminuria and chronic kidney disease as risk factors for cardiovascular disease. Nephrol Dial Transplant. 2006;21:2366-2374.

    Not in our library10.1093/ndt/gfl309

  107. 107.

    Go AS, Chertow GM, Fan D, McCulloch CE, Hsu CY. Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med. 2004;351:1296-1305.

    Not in our library10.1056/nejmoa041031

  108. 108.

    Gameiro J, Neves JB, Rodrigues N, et al. Acute kidney injury, long-term renal function and mortality in patients undergoing major abdominal surgery: a cohort analysis. Clin Kidney J. 2016;9(2):192-200.

    Not in our library10.1093/ckj/sfv144

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