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Atom transfer radical polymer-modified paper for improvement in protein fixation in paper-based ELISA

Lu Qi, Aihong Zhang, Yu Wang and 2 more

BMC Chemistry · 2019

doi:10.1186/s13065-019-0622-7 (opens in a new tab)

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Abstract

A newly modified paper-based enzyme-linked immunosorbent assay (P-ELISA) was established by immobilizing more proteins on the paper surface through an atom transfer radical polymerization (ATRP) reaction. In addition, introducing graphene oxide (GO) sheets, Au nanoparticles (AuNps) and two primary antibodies (Ab1s) led to signal amplification and cost reduction.

Abstract licence: CC BY-NC-ND

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