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Behavioral and neural network abnormalities in human APP transgenic mice resemble those of App knock-in mice and are modulated by familial Alzheimer’s disease mutations but not by inhibition of BACE1

Erik C. B. Johnson, Kaitlyn Ho, Gui-Qiu Yu and 10 more

Molecular Neurodegeneration · 2020

doi:10.1186/s13024-020-00393-5

References 166

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Evidence that the rab5 effector APPL1 mediates APP-βCTF-induced dysfunction of endosomes in Down syndrome and Alzheimer’s disease · 2015
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Neuroinflammation and Neuronal Loss Precede Aβ Plaque Deposition in the hAPP-J20 Mouse Model of Alzheimer’s Disease · 2013
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All 166 references

Cited by papers we hold 1

Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia · 2022
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