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How can nanotechnology help to combat COVID-19? Opportunities and urgent need

Estefânia V. R. Campos, Anderson E. S. Pereira, Jhones Luiz de Oliveira and 4 more

Journal of Nanobiotechnology · 2020 · Review · CC BY

doi:10.1186/s12951-020-00685-4

Abstract

Incidents of viral outbreaks have increased at an alarming rate over the past decades. The most recent human coronavirus known as COVID-19 (SARS-CoV-2) has already spread around the world and shown R 0 values from 2.2 to 2.68. However, the ratio between mortality and number of infections seems to be lower in this case in comparison to other human coronaviruses (such as severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV)). These outbreaks have tested the limits of healthcare systems and have posed serious questions about management using conventional therapies and diagnostic tools. In this regard, the use of nanotechnology offers new opportunities for the development of novel strategies in terms of prevention, diagnosis and treatment of COVID-19 and other viral infections. In this review, we discuss the use of nanotechnology for COVID-19 virus management by the development of nano-based materials, such as disinfectants, personal protective equipment, diagnostic systems and nanocarrier systems, for treatments and vaccine development, as well as the challenges and drawbacks that need addressing.

References 208

  1. 1.

    Dhama K, Pawaiya RVS, Chakrabort S, Tiwari R, Saminathan M, Verma AK. Coronavirus infection in equines: a review. Asian J Anim Vet Adv. 2014;9:164-176.

    Not in our library

  2. 2.
  3. 3.
  4. 4.

    Li Q, Guan X, Wu P, Wang X, Zhou L, Tong Y, et al. Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia. N Engl J Med. 2020;382:1199-1207.

    Not in our library10.1056/nejmoa2001316

  5. 5.

    Chen N, Zhou M, Dong X, Qu J, Gong F, Han Y, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet. 2020;395:507-513.

    Not in our library10.1016/s0140-6736(20)30211-7

  6. 6.

    Liu Y, Gayle AA, Wilder-Smith A, Rocklöv J. The reproductive number of COVID-19 is higher compared to SARS coronavirus. J Travel Med. 2020;27:taaa021.

    Not in our library10.1093/jtm/taaa021

  7. 7.

    Cucinotta D, Vanelli M. WHO declares COVID-19 a pandemic. Acta Bio Medica Atenei Parmensis. 2020;91:157-160.

    Not in our library10.23750/abm.v91i1.9397

  8. 8.

    Cui J, Li F, Shi Z-L. Origin and evolution of pathogenic coronaviruses. Nat Rev Microbiol. 2019;17:181-192.

    Not in our library10.1038/s41579-018-0118-9

  9. 9.

    Lu R, Zhao X, Li J, Niu P, Yang B, Wu H, et al. Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. Lancet. 2020;395:565-574.

    Not in our library10.1016/s0140-6736(20)30251-8

  10. 10.
  11. 11.

    Wan Y, Shang J, Graham R, Baric RS, Li F. Receptor recognition by the novel coronavirus from Wuhan: an analysis based on decade-long structural studies of SARS coronavirus. J Virol. 2020;94:e00127-20.

    Not in our library10.1128/jvi.00127-20

  12. 12.

    Hoffmann M, Kleine-Weber H, Krüger N, Müller M, Drosten C, Pöhlmann S. The novel coronavirus 2019 (2019-nCoV) uses the SARS-coronavirus receptor ACE2 and the cellular protease TMPRSS2 for entry into target cells. Mol Biol. 2020.

    Not in our library10.1101/2020.01.31.929042

  13. 13.

    Wrapp D, Wang N, Corbett KS, Goldsmith JA, Hsieh C-L, Abiona O, et al. Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation. Science. 2020;367:1260-1263.

    Not in our library10.1126/science.abb2507

  14. 14.

    Letko M, Marzi A, Munster V. Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses. Nat Microbiol. 2020;5:562-569.

    Not in our library10.1038/s41564-020-0688-y

  15. 15.
  16. 16.

    Zumla A, Hui DS, Azhar EI, Memish ZA, Maeurer M. Reducing mortality from 2019-nCoV: host-directed therapies should be an option. Lancet. 2020;395:e35-e36.

    Not in our library10.1016/s0140-6736(20)30305-6

  17. 17.
  18. 18.

    Vellingiri B, Jayaramayya K, Iyer M, Narayanasamy A, Govindasamy V, Giridharan B, et al. COVID-19: a promising cure for the global panic. Sci Total Environ. 2020;725:138277.

    Not in our library10.1016/j.scitotenv.2020.138277

  19. 19.

    Hui L, Yeming W, Jiuyang X, Bin C. Potential antiviral therapeutics for 2019 Novel Coronavirus. Chin J Tuberc Respir Dis. 2020;43:170-172.

    Not in our library10.3760/cma.j.issn.1001-0939.2020.03.004

  20. 20.

    Zhang J, Zhou L, Yang Y, Peng W, Wang W, Chen X. Therapeutic and triage strategies for 2019 novel coronavirus disease in fever clinics. Lancet Respir Med. 2020;8:e11-e12.

    Not in our library10.1016/s2213-2600(20)30071-0

  21. 21.

    Xia B, Kang X. Activation and maturation of SARS-CoV main protease. Protein Cell. 2011;2:282-290.

    Not in our library10.1007/s13238-011-1034-1

  22. 22.

    Kang S, Peng W, Zhu Y, Lu S, Zhou M, Lin W, et al. Recent progress in understanding 2019 novel coronavirus (SARS-CoV-2) associated with human respiratory disease: detection, mechanisms and treatment. Int J Antimicrob Agents. 2020;55:105950.

    Not in our library10.1016/j.ijantimicag.2020.105950

  23. 23.

    Strasfeld L, Chou S. Antiviral drug resistance: mechanisms and clinical implications. Infect Dis Clin N Am. 2010;24:413-437.

    Not in our library10.1016/j.idc.2010.01.001

  24. 24.

    Jackman JA, Lee J, Cho N-J. Nanomedicine for infectious disease applications: innovation towards broad-spectrum treatment of viral infections. Small. 2016;12:1133-1139.

    Not in our library10.1002/smll.201500854

  25. 25.

    Chen W-H, Strych U, Hotez PJ, Bottazzi ME. The SARS-CoV-2 vaccine pipeline: an overview. Curr Trop Med Rep. 2020;7:61-64.

    Not in our library10.1007/s40475-020-00201-6

  26. 26.

    Revuelta-Herrero JL, Chamorro-de-Vega E, Rodríguez-González CG, Alonso R, Herranz-Alonso A, Sanjurjo-Sáez M. Effectiveness, safety, and costs of a treatment switch to dolutegravir plus rilpivirine dual therapy in treatment-experienced HIV patients. Ann Pharmacother. 2018;52:11-18.

    Not in our library10.1177/1060028017728294

  27. 27.

    Mohammadi Pour P, Fakhri S, Asgary S, Farzaei MH, Echeverría J. The signaling pathways, and therapeutic targets of antiviral agents: focusing on the antiviral approaches and clinical perspectives of anthocyanins in the management of viral diseases. Front Pharmacol. 2019;10:1207.

    Not in our library10.3389/fphar.2019.01207

  28. 28.

    Lembo D, Donalisio M, Civra A, Argenziano M, Cavalli R. Nanomedicine formulations for the delivery of antiviral drugs: a promising solution for the treatment of viral infections. Expert Opin Drug Deliv. 2018;15:93-114.

    Not in our library10.1080/17425247.2017.1360863

  29. 29.

    Singh L, Kruger HG, Maguire GEM, Govender T, Parboosing R. The role of nanotechnology in the treatment of viral infections. Ther Adv Infect Dis. 2017;4:105-131.

    Not in our library10.1177/2049936117713593

  30. 30.

    Szunerits S, Barras A, Khanal M, Pagneux Q, Boukherroub R. Nanostructures for the inhibition of viral infections. Molecules. 2015;20:14051-14081.

    Not in our library10.3390/molecules200814051

  31. 31.
  32. 32.
  33. 33.
  34. 34.

    Fornaguera C, García-Celma MJ. Personalized nanomedicine: a revolution at the nanoscale. J Personal Med. 2017;7:12-20.

    Not in our library10.3390/jpm7040012

  35. 35.

    Ben-Shabat S, Yarmolinsky L, Porat D, Dahan A. Antiviral effect of phytochemicals from medicinal plants: applications and drug delivery strategies. Drug Deliv Transl Res. 2020;10:354-367.

    Not in our library10.1007/s13346-019-00691-6

  36. 36.
  37. 37.
  38. 38.

    Watkins R, Wu L, Zhang C, Davis RM, Xu B. Natural product-based nanomedicine: recent advances and issues. Int J Nanomedicine. 2015;10:6055-6074.

    Not in our library10.2147/ijn.s92162

  39. 39.

    Mokhtarzadeh A, Eivazzadeh-Keihan R, Pashazadeh P, Hejazi M, Gharaatifar N, Hasanzadeh M, et al. Nanomaterial-based biosensors for detection of pathogenic virus. Trends Anal Chem. 2017;97:445-457.

    Not in our library10.1016/j.trac.2017.10.005

  40. 40.

    Kizek R, Krejcova L, Michalek P, Merlos Rodrigo M, Heger Z, Krizkova S, et al. Nanoscale virus biosensors: state of the art. NDD. 2015;4:47-66.

    Not in our library

  41. 41.
  42. 42.

    Vijayan V, Mohapatra A, Uthaman S, Park IK. Recent advances in nanovaccines using biomimetic immunomodulatory materials. Pharmaceutics. 2019;11:534.

    Not in our library10.3390/pharmaceutics11100534

  43. 43.

    Luo R, Fang L, Jin H, Wang D, An K, Xu N, et al. Label-free quantitative phosphoproteomic analysis reveals differentially regulated proteins and pathway in PRRSV-Infected Pulmonary Alveolar Macrophages. J Proteome Res. 2014;13:1270-1280.

    Not in our library10.1021/pr400852d

  44. 44.

    Pan H, Zhang P, Gao D, Zhang Y, Li P, Liu L, et al. Noninvasive visualization of respiratory viral infection using bioorthogonal conjugated near-infrared-emitting quantum dots. ACS Nano. 2014;8:5468-5477.

    Not in our library10.1021/nn501028b

  45. 45.

    Zhang Y, Ke X, Zheng Z, Zhang C, Zhang Z, Zhang F, et al. Encapsulating quantum dots into enveloped virus in living cells for tracking virus infection. ACS Nano. 2013;7:3896-3904.

    Not in our library10.1021/nn305189n

  46. 46.

    Kramer A, Assadian O. Survival of microorganisms on inanimate surfaces. In: Use of biocidal surfaces for reduction of healthcare acquired infections. Springer International Publishing AG; 2014. p. 7–26.

    Not in our library

  47. 47.
  48. 48.

    Lee W-S, Hsieh T-C, Shiau JC, Ou T-Y, Chen F-L, Liu Y-H, et al. Bio-Kil, a nano-based disinfectant, reduces environmental bacterial burden and multidrug-resistant organisms in intensive care units. J Microbiol Immunol Infect. 2017;50:737-746.

    Not in our library10.1016/j.jmii.2016.04.008

  49. 49.

    Karunanayake LI, Waniganayake YC, Gunawardena KDN, Padmaraja SAD, Peter D, Jayasekera R, et al. Use of silicon nanoparticle surface coating in infection control: experience in a tropical healthcare setting. Infect Dis Health. 2019;24:201-207.

    Not in our library10.1016/j.idh.2019.06.006

  50. 50.

    Ortí-Lucas RM, Muñoz-Miguel J. Effectiveness of surface coatings containing silver ions in bacterial decontamination in a recovery unit. Antimicrob Resist Infect Control. 2017;6:61.

    Not in our library10.1186/s13756-017-0217-9

  51. 51.

    Si Y, Zhang Z, Wu W, Fu Q, Huang K, Nitin N, et al. Daylight-driven rechargeable antibacterial and antiviral nanofibrous membranes for bioprotective applications. Sci Adv. 2018;4:eaar5931.

    Not in our library10.1126/sciadv.aar5931

  52. 52.

    Herron JBT, Hay-David AGC, Gilliam AD, Brennan PA. Personal protective equipment and Covid 19—a risk to healthcare staff? Br J Oral Maxillofac Surg. 2020;58(5):500-502.

    Not in our library10.1016/j.bjoms.2020.04.015

  53. 53.

    van Doremalen N, Bushmaker T, Morris DH, Holbrook MG, Gamble A, Williamson BN, et al. Aerosol and surface stability of SARS-CoV-2 as compared with SARS-CoV-1. N Engl J Med. 2020;382:1564-1567.

    Not in our library10.1056/nejmc2004973

  54. 54.

    Kampf G. Potential role of inanimate surfaces for the spread of coronaviruses and their inactivation with disinfectant agents. Infect Prev Pract. 2020;2:100044.

    Not in our library10.1016/j.infpip.2020.100044

  55. 55.
  56. 56.

    Kapoor A, Saha R. Hand washing agents and surface disinfectants in times of Coronavirus (COVID-19) outbreak. Indian J Community Health. 2020;32:225-227.

    Not in our library

  57. 57.

    Huang H, Fan C, Li M, Nie H-L, Wang F-B, Wang H, et al. COVID-19: a call for physical scientists and engineers. ACS Nano. 2020;14(4):3747-3754.

    Not in our library10.1021/acsnano.0c02618

  58. 58.

    Querido MM, Aguiar L, Neves P, Pereira CC, Teixeira JP. Self-disinfecting surfaces and infection control. Colloids Surf B Biointerfaces. 2019;178:8-21.

    Not in our library10.1016/j.colsurfb.2019.02.009

  59. 59.

    Geyer F, D’Acunzi M, Sharifi-Aghili A, Saal A, Gao N, Kaltbeitzel A, et al. When and how self-cleaning of superhydrophobic surfaces works. Sci Adv. 2020;6:eaaw9727.

    Not in our library10.1126/sciadv.aaw9727

  60. 60.

    Dalawai SP, Saad Aly MA, Latthe SS, Xing R, Sutar RS, Nagappan S, et al. Recent advances in durability of superhydrophobic self-cleaning technology: a critical review. Prog Org Coat. 2020;138:105381.

    Not in our library

  61. 61.

    Dyshlyuk L, Babich O, Ivanova S, Vasilchenco N, Prosekov A, Sukhikh S. Suspensions of metal nanoparticles as a basis for protection of internal surfaces of building structures from biodegradation. Case Stud Constr Mater. 2020;12:e00319.

    Not in our library

  62. 62.

    Rai M, Deshmukh SD, Ingle AP, Gupta IR, Galdiero M, Galdiero S. Metal nanoparticles: the protective nanoshield against virus infection. Crit Rev Microbiol. 2016;42:46-56.

    Not in our library10.3109/1040841x.2013.879849

  63. 63.

    Vaze N, Pyrgiotakis G, McDevitt J, Mena L, Melo A, Bedugnis A, et al. Inactivation of common hospital acquired pathogens on surfaces and in air utilizing engineered water nanostructures (EWNS) based nano-sanitizers. Nanomed Nanotechnol Biol Med. 2019;18:234-242.

    Not in our library10.1016/j.nano.2019.03.003

  64. 64.

    StatNano. Coronavirus: nanotech surface sanitizes milan with nanomaterials remaining self-sterilized for years | STATNANO. 2020. https://statnano.com//news/67531/Coronavirus-Nanotech-Surface-Sanitizes-Milan-with-Nanomaterials-Remaining-Self-sterilized-for-Years. Accessed 28 Apr 2020.

    Not in our library

  65. 65.

    StatNano. Mineral nanocrystal-based coating activated by light kills coronavirus | STATNANO. 2020. https://statnano.com/news/67583/Mineral-Nanocrystal-based-Coating-Activated-by-Light-Kills-Coronavirus. Accessed 7 Aug 2020.

    Not in our library

  66. 66.

    Chan WCW. Nano research for COVID-19. ACS Nano. 2020;14:3719-3720.

    Not in our library10.1021/acsnano.0c02540

  67. 67.

    Abo-zeid Y, Urbanowicz RA, Thomson BJ, Irving WL, Tarr AW, Garnett MC. Enhanced nanoparticle uptake into virus infected cells: could nanoparticles be useful in antiviral therapy? Int J Pharm. 2018;547:572-581.

    Not in our library10.1016/j.ijpharm.2018.06.027

  68. 68.

    Li Y, Lin Z, Zhao M, Xu T, Wang C, Hua L, et al. Silver nanoparticle based codelivery of oseltamivir to inhibit the activity of the H1N1 Influenza Virus through ROS-mediated signaling pathways. ACS Appl Mater Interfaces. 2016;8:24385-24393.

    Not in our library10.1021/acsami.6b06613

  69. 69.

    Kim J, Yeom M, Lee T, Kim H-O, Na W, Kang A, et al. Porous gold nanoparticles for attenuating infectivity of influenza A virus. J Nanobiotechnol. 2020;18:54.

    Not in our library10.1186/s12951-020-00611-8

  70. 70.

    Sun B, Zhang M, He Z, Zheng L, Shen J, Ni Y. Towards greener and more sustainable cellulose-based hand sanitizer products. JB&B. 2017;2:56-60.

    Not in our library

  71. 71.

    Park S, Ko Y-S, Lee SJ, Lee C, Woo K, Ko G. Inactivation of influenza A virus via exposure to silver nanoparticle-decorated silica hybrid composites. Environ Sci Pollut Res. 2018;25:27021-27030.

    Not in our library10.1007/s11356-018-2620-z

  72. 72.

    Neal J, Sirsat S. Titanium dioxide nanoparticles as an environmental sanitizing agent. J Microb Biochem Technol. 2015;07:61-64.

    Not in our library

  73. 73.

    Joost U, Juganson K, Visnapuu M, Mortimer M, Kahru A, Nõmmiste E, et al. Photocatalytic antibacterial activity of nano-TiO2 (anatase)-based thin films: effects on Escherichia coli cells and fatty acids. J Photochem Photobiol B. 2015;142:178-185.

    Not in our library10.1016/j.jphotobiol.2014.12.010

  74. 74.

    Wei G, Nguyen D, Reghu S, Li J, Chua C, Ishida Y, et al. Fast-bactericidal effect of polyion complex nanoparticles on gram-negative bacteria. ACS Appl Nano Mater. 2020;3:2654-2664.

    Not in our library

  75. 75.

    Vandhana T, Clement Lourduraj AJ. Biogenic synthesis of Mn-Ag co-doped FeO (Fe1-2xMnxAgx) nanoparticles: as an effective disinfectant and anticancer agent. Inorg Chem Commun. 2020;112:107712.

    Not in our library

  76. 76.

    SZALAY SFD. Skin sanitizer compositions comprising alcohol based emulsion. 2013. https://patents.google.com/patent/EP2654670A2/en. Accessed 26 Apr 2020.

    Not in our library

  77. 77.

    Hu K, Liu H. Preparation method and application of essential oil and plga (poly(lactic-co-glycolic acid)) compounded shell-core structure nanoparticles. CN109568180A. 2019. https://worldwide.espacenet.com/patent/search/family/065924361/publication/CN109568180A?q=CN109568180A&queryLang=en%3Ade%3Afr.

    Not in our library

  78. 78.

    Chiattello ML, Oman M. Polymer-based antimicrobial compositions and methods of use thereof. EP3493676A1. 2019. https://worldwide.espacenet.com/patent/search/family/061011855/publication/EP3493676A1?q=EP3493676A1&queryLang=en%3Ade%3Afr.

    Not in our library

  79. 79.

    Jones S, Stellacci F. Virucidal compounds and uses thereof. EP3487508A1. 2019. https://worldwide.espacenet.com/patent/search/family/056550084/publication/EP3487508A1?q=EP3487508A1&queryLang=en%3Ade%3Afr.

    Not in our library

  80. 80.

    Shivdas HP, Vitthal MR. Environment-friendly silver nanocomposite and method for same. IN1426/MUM/2014, 2015. https://www.quickcompany.in/patents/environment-friendly-silver-nanocomposite-and-method-for-same.

    Not in our library

  81. 81.

    GONDAL MA, Dastageer MA, Khalil AB, Siddique RG, Baig U. Method of forming a photocatalyst and disinfecting a fluid. 2019 https://patents.google.com/patent/US10421672B2/en. Accessed 26 Apr 2020.

    Not in our library

  82. 82.

    Grossman C, Ngo M, Wysocki R. Composition and method to form a self decontaminating surface. 2019. https://patents.google.com/patent/US10421870B2/en. Accessed 26 Apr 2020.

    Not in our library

  83. 83.

    Gutiérrez GL. Nanoparticulate titanium dioxide nanomaterial modified with functional groups and with citric extracts adsorbed on the surface, for the removal of a wide range of microorganisms. 2019. https://patents.google.com/patent/US10342840B2/en. Accessed 19 Apr 2020.

    Not in our library

  84. 84.

    Rösch A, Schaefer C. Metal Dispersion with Increased Stability. EP3368204A1. 2018. https://worldwide.espacenet.com/patent/search/family/057130386/publication/EP3368204A1?q=EP3368204A1&queryLang=en%3Ade%3Afr.

    Not in our library

  85. 85.

    Liu Y, Sun W. Preparation method of nanometer silver/quaternary ammonium salt composite sanitizer. CN108391673A, 2018. https://worldwide.espacenet.com/patent/search/family/063091462/publication/CN108391673A?q=CN108391673A&queryLang=en%3Ade%3Afr.

    Not in our library

  86. 86.

    CDC. Coronavirus disease 2019 (COVID-19)—transmission. Centers for Disease Control and Prevention. 2020. Available from: https://www.cdc.gov/coronavirus/2019-ncov/prevent-getting-sick/how-covid-spreads.html. Accessed 11 Aug 2020.

    Not in our library

  87. 87.

    Conlon M. A facemask having one or more nanofiber layers. 2014. https://patents.google.com/patent/WO2014143039A1/en. Accessed 27 Apr 2020.

    Not in our library

  88. 88.

    Lustenberger F. Nanofiber filtering material for disposable/reusable respirators. 2016. https://patents.google.com/patent/US9446547B2/en. Accessed 27 Apr 2020.

    Not in our library

  89. 89.

    Ren G, Oxford PJS, Reip PW, Lambkin-Williams R, Mann A. Anti-viral formulations nanomaterials and nanoparticles. 2013. https://patents.google.com/patent/US20130091611/de. Accessed 27 Apr 2020.

    Not in our library

  90. 90.

    Yetisen AK, Qu H, Manbachi A, Butt H, Dokmeci MR, Hinestroza JP, et al. Nanotechnology in textiles. ACS Nano. 2016;10:3042-3068.

    Not in our library10.1021/acsnano.5b08176

  91. 91.

    Spagnol C, Fragal EH, Pereira AGB, Nakamura CV, Muniz EC, Follmann HDM, et al. Cellulose nanowhiskers decorated with silver nanoparticles as an additive to antibacterial polymers membranes fabricated by electrospinning. J Colloid Interface Sci. 2018;531:705-715.

    Not in our library10.1016/j.jcis.2018.07.096

  92. 92.

    Mansi A, Boccuni F, Iavicoli S. Nanomaterials as a new opportunity for protecting workers from biological risk. Ind Health. 2019;57:668-675.

    Not in our library10.2486/indhealth.2018-0197

  93. 93.

    El-Nahhal IM, Salem J, Anbar R, Kodeh FS, Elmanama A. Preparation and antimicrobial activity of ZnO-NPs coated cotton/starch and their functionalized ZnO-Ag/cotton and Zn(II) curcumin/cotton materials. Sci Rep. 2020;10:5410.

    Not in our library10.1038/s41598-020-61306-6

  94. 94.

    Srinivas AD, Peng C, Mittal AC, Agarwal P. Surfaces having particles and related methods. 2014. https://patents.google.com/patent/US20140041905A1/en. Accessed 27 Apr 2020.

    Not in our library

  95. 95.

    Elston DM. Occupational skin disease among health care workers during the coronavirus (COVID-19) epidemic. J Am Acad Dermatol. 2020;82:1085-1086.

    Not in our library10.1016/j.jaad.2020.03.012

  96. 96.

    Kanovsky M. Antimicrobial fabric materials for use in safety masks and personal protection clothing. 2016. https://patents.google.com/patent/WO2016125173A1/no. Accessed 27 Apr 2020.

    Not in our library

  97. 97.

    Clement S. Kupfer(II)enthaltende Formmasse aus Polyester, ihre Herstellung und Verwendung. 2008. https://patents.google.com/patent/DE102007003649A1/de. Accessed 10 Aug 2020.

    Not in our library

  98. 98.

    ФУДЖИMOPИ И, ДЖИКИXИPA И, CATO T, ФУКУИ Й, HAКAЯMA Ц. Virus inactivating cloth. 2015. https://patents.google.com/patent/RU2550922C2/en. Accessed 27 Apr 2020.

    Not in our library

  99. 99.

    Deshmukh SP, Patil SM, Mullani SB, Delekar SD. Silver nanoparticles as an effective disinfectant: a review. Mater Sci Eng C. 2019;97:954-965.

    Not in our library10.1016/j.msec.2018.12.102

  100. 100.

    Amigoni S, Josse D, Devers T, Zenerino A, Guittard F, de Givenchy ET, et al. Polymerised cerium oxide nanoparticles in an active or bioactive network, protective topical treatments, methods for preparation thereof and uses thereof. 2018. https://patents.google.com/patent/US10155869B2/en. Accessed 27 Apr 2020.

    Not in our library

  101. 101.

    Ballard RL, Anneaux BL, Manasco JL, Garner DP, Hao P. Electrospun porous media. 2013. https://patents.google.com/patent/US20130197664A1/en. Accessed 27 Apr 2020.

    Not in our library

  102. 102.

    고군호, 박종철. Face mask having nano fiber layer. 2012. https://patents.google.com/patent/KR101130788B1/en. Accessed 23 June 2020.

    Not in our library

  103. 103.

    Kwak JH. Antiviral treatment method, antiviral filter, and mask having same. 2019. https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2019160261. Accessed 23 June 2020.

    Not in our library

  104. 104.

    Udugama B, Kadhiresan P, Kozlowski HN, Malekjahani A, Osborne M, Li VYC, et al. Diagnosing COVID-19: the disease and tools for detection. ACS Nano. 2020;14:3822-3835.

    Not in our library10.1021/acsnano.0c02624

  105. 105.

    Draz MS, Shafiee H. Applications of gold nanoparticles in virus detection. Theranostics. 2018;8:1985-2017.

    Not in our library10.7150/thno.23856

  106. 106.

    Chen L, Liang J. An overview of functional nanoparticles as novel emerging antiviral therapeutic agents. Mater Sci Eng C. 2020;112:110924.

    Not in our library10.1016/j.msec.2020.110924

  107. 107.

    Cheng X, Chen G, Rodriguez WR. Micro- and nanotechnology for viral detection. Anal Bioanal Chem. 2009;393:487-501.

    Not in our library10.1007/s00216-008-2514-x

  108. 108.

    Waris A, Ali M, Khan AU, Ali A, Baset A. Exploring pathophysiology of COVID-19 infection: faux espoir and dormant therapeutic options. Int J Clin Virol. 2020;4:065-070.

    Not in our library

  109. 109.

    Moitra P, Alafeef M, Dighe K, Frieman MB, Pan D. Selective naked-eye detection of SARS-CoV-2 mediated by N gene targeted antisense oligonucleotide capped plasmonic nanoparticles. ACS Nano. 2020;14:7617-7627.

    Not in our library10.1021/acsnano.0c03822

  110. 110.

    Halfpenny KC, Wright DW. Nanoparticle detection of respiratory infection: nanoparticle detection of respiratory infection. WIREs Nanomed Nanobiotechnol. 2010;2:277-290.

    Not in our library10.1002/wnan.83

  111. 111.

    Talebian S, Wallace GG, Schroeder A, Stellacci F, Conde J. Nanotechnology-based disinfectants and sensors for SARS-CoV-2. Nat Nanotechnol. 2020;15:618-621.

    Not in our library10.1038/s41565-020-0751-0

  112. 112.

    Layqah LA, Eissa S. An electrochemical immunosensor for the corona virus associated with the Middle East respiratory syndrome using an array of gold nanoparticle-modified carbon electrodes. Microchim Acta. 2019;186:224.

    Not in our library10.1007/s00604-019-3345-5

  113. 113.

    Kim H, Park M, Hwang J, Kim JH, Chung D-R, Lee K, et al. Development of label-free colorimetric assay for MERS-CoV using gold nanoparticles. ACS Sens. 2019;4:1306-1312.

    Not in our library10.1021/acssensors.9b00175

  114. 114.
  115. 115.
  116. 116.

    Zhao Z, Cui H, Song W, Ru X, Zhou W, Yu X. A simple magnetic nanoparticles-based viral RNA extraction method for efficient detection of SARS-CoV-2. Mol Biol. 2020.

    Not in our library10.1101/2020.02.22.961268

  117. 117.

    Brazilchuck N. From thousands of tiny magnetic balls to 150,000 COVID-19 tests per week. Norwegian SciTech News. 2020. https://norwegianscitechnews.com/2020/04/from-thousands-of-tiny-magnetic-balls-to-150000-covid-19-tests-per-week/. Accessed 10 Aug 2020.

    Not in our library

  118. 118.

    Seo G, Lee G, Kim MJ, Baek S-H, Choi M, Ku KB, et al. Rapid detection of COVID-19 causative virus (SARS-CoV-2) in Human nasopharyngeal swab specimens using field-effect transistor-based biosensor. ACS Nano. 2020;14:5135-5142.

    Not in our library10.1021/acsnano.0c02823

  119. 119.

    Santiago I. Trends and innovations in biosensors for COVID-19 mass testing. ChemBioChem. 2020.

    Not in our library10.1002/cbic.202000250

  120. 120.

    Nguyen TM, Zhang Y, Pandolfi PP. Virus against virus: a potential treatment for 2019-nCov (SARS-CoV-2) and other RNA viruses. Cell Res. 2020;30:189-190.

    Not in our library10.1038/s41422-020-0290-0

  121. 121.

    Solaimuthu A, Vijayan AN, Murali P, Korrapati PS. Nano-biosensors and their relevance in tissue engineering. Curr Opin Biomed Eng. 2020;13:84-93.

    Not in our library

  122. 122.

    Zhu X, Wang X, Han L, Chen T, Wang L, Li H, et al. Reverse transcription loop-mediated isothermal amplification combined with nanoparticles-based biosensor for diagnosis of COVID-19. 2020. 10.1101/2020.03.17.20037796.

    Not in our library10.1016/j.bios.2020.112437

  123. 123.

    Chen Z, Zhang Z, Zhai X, Li Y, Lin L, Zhao H, et al. Rapid and Sensitive detection of anti-SARS-CoV-2 IgG, using lanthanide-doped nanoparticles-based lateral flow immunoassay. Anal Chem. 2020;92:7226-7231.

    Not in our library10.1021/acs.analchem.0c00784

  124. 124.

    Qiu G, Gai Z, Tao Y, Schmitt J, Kullak-Ublick GA, Wang J. Dual-functional plasmonic photothermal biosensors for highly accurate severe acute respiratory syndrome coronavirus 2 detection. ACS Nano. 2020;14:5268-5277.

    Not in our library10.1021/acsnano.0c02439

  125. 125.

    Somvanshi SB, Kharat PB, Saraf TS, Somwanshi SB, Shejul SB, Jadhav KM. Multifunctional nano-magnetic particles assisted viral RNA-extraction protocol for potential detection of COVID-19. Mater Res Innov. 2020;24:1-6.

    Not in our library

  126. 126.

    Wang M, Fu A, Hu B, Tong Y, Liu R, Liu Z, et al. Nanopore targeted sequencing for the accurate and comprehensive detection of SARS-CoV-2 and other respiratory viruses. Small. 2020;16(32):2002169.

    Not in our library10.1002/smll.202002169

  127. 127.

    Huang L, Ding L, Zhou J, Chen S, Chen F, Zhao C, et al. One-step rapid quantification of SARS-CoV-2 virus particles via low-cost nanoplasmonic sensors in generic microplate reader and point-of-care device. BioRxiv. 2020;142373:1-18.

    Not in our library10.1016/j.bios.2020.112685

  128. 128.

    Sanders JM, Monogue ML, Jodlowski TZ, Cutrell JB. Pharmacologic treatments for coronavirus disease 2019 (COVID-19): a review. JAMA. 2020;323(18):1824-1836.

    Not in our library10.1001/jama.2020.6019

  129. 129.

    Salvi R, Patankar P. Emerging pharmacotherapies for COVID-19. Biomed Pharmacother. 2020;128:110267.

    Not in our library10.1016/j.biopha.2020.110267

  130. 130.

    García-Serradilla M, Risco C, Pacheco B. Drug repurposing for new, efficient, broad spectrum antivirals. Virus Res. 2019;264:22-31.

    Not in our library10.1016/j.virusres.2019.02.011

  131. 131.
  132. 132.
  133. 133.
  134. 134.
  135. 135.

    Clercq ED, Li G. approved antiviral drugs over the past 50 years. Clin Microbiol Rev. 2016;29:695-747.

    Not in our library10.1128/cmr.00102-15

  136. 136.

    Al-Bari MAA. Chloroquine analogues in drug discovery: new directions of uses, mechanisms of actions and toxic manifestations from malaria to multifarious diseases. J Antimicrob Chemother. 2015;70:1608-1621.

    Not in our library10.1093/jac/dkv018

  137. 137.

    Thomas E, Ghany MG, Liang TJ. The application and mechanism of action of ribavirin in therapy of hepatitis C. Antivir Chem Chemother. 2012;23:1-12.

    Not in our library10.3851/imp2125

  138. 138.

    Sofias AM, Andreassen T, Hak S. Nanoparticle ligand-decoration procedures affect in vivo interactions with immune cells. Mol Pharm. 2018;15:5754-5761.

    Not in our library10.1021/acs.molpharmaceut.8b00908

  139. 139.

    Sun X, Wang T, Cai D, Hu Z, Chen J, Liao H, et al. Cytokine storm intervention in the early stages of COVID-19 pneumonia. Cytokine Growth Factor Rev. 2020;53:38-42.

    Not in our library10.1016/j.cytogfr.2020.04.002

  140. 140.

    Ye Q, Wang B, Mao J. The pathogenesis and treatment of the ‘Cytokine Storm’ in COVID-19. J Infect. 2020;80:607-613.

    Not in our library10.1016/j.jinf.2020.03.037

  141. 141.

    Leuschner F, Dutta P, Gorbatov R, Novobrantseva TI, Donahoe JS, Courties G, et al. Therapeutic siRNA silencing in inflammatory monocytes in mice. Nat Biotechnol. 2011;29:1005-1010.

    Not in our library10.1038/nbt.1989

  142. 142.

    Testori A. The “perfect cytokine storm” of covID-19. Mayo Clin Proc. 2020. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256537/.

    Not in our library10.1016/j.mayocp.2020.05.015

  143. 143.

    Khalvati B, Sheikhsaran F, Sharifzadeh S, Kalantari T, Behzad Behbahani A, Jamshidzadeh A, et al. Delivery of plasmid encoding interleukin-12 gene into hepatocytes by conjugated polyethylenimine-based nanoparticles. Artif Cells Nanomed Biotechnol. 2017;45:1036-1044.

    Not in our library10.1080/21691401.2016.1202256

  144. 144.

    Zeng L, Ma W, Shi L, Chen X, Wu R, Zhang Y, et al. Poly(lactic-co-glycolic acid) nanoparticle-mediated interleukin-12 delivery for the treatment of diabetic retinopathy. IJN. 2019;14:6357-6369.

    Not in our library10.2147/ijn.s214727

  145. 145.

    Gao H, Xiong Y, Zhang S, Yang Z, Cao S, Jiang X. RGD and interleukin-13 peptide functionalized nanoparticles for enhanced glioblastoma cells and neovasculature dual targeting delivery and elevated tumor penetration. Mol Pharm. 2014;11:1042-1052.

    Not in our library10.1021/mp400751g

  146. 146.
  147. 147.

    Dormont F, Brusini R, Cailleau C, Reynaud F, Peramo A, Gendron A, et al. Squalene-based multidrug nanoparticles for improved mitigation of uncontrolled inflammation in rodents. Sci Adv. 2020;6:eaaz5466.

    Not in our library10.1126/sciadv.aaz5466

  148. 148.

    Loutfy SA, Elberry MH, Farroh KY, Mohamed HT, Mohamed AA, Mohamed EB, et al. Antiviral activity of chitosan nanoparticles encapsulating curcumin against hepatitis C virus genotype 4a in human hepatoma cell lines. IJN. 2020;15:2699-2715.

    Not in our library10.2147/ijn.s241702

  149. 149.

    Dey P, Bergmann T, Cuellar-Camacho JL, Ehrmann S, Chowdhury MS, Zhang M, et al. Multivalent flexible nanogels exhibit broad-spectrum antiviral activity by blocking virus entry. ACS Nano. 2018;12:6429-6442.

    Not in our library10.1021/acsnano.8b01616

  150. 150.

    Hendricks GL, Weirich KL, Viswanathan K, Li J, Shriver ZH, Ashour J, et al. Sialylneolacto-N-tetraose c (LSTc)-bearing liposomal decoys capture influenza A virus. J Biol Chem. 2013;288:8061-8073.

    Not in our library10.1074/jbc.m112.437202

  151. 151.

    Łoczechin A, Séron K, Barras A, Giovanelli E, Belouzard S, Chen Y-T, et al. Functional carbon quantum dots as medical countermeasures to human coronavirus. ACS Appl Mater Interfaces. 2019;11:42964-42974.

    Not in our library10.1021/acsami.9b15032

  152. 152.

    Hu C-MJ, Chen Y-T, Fang Z-S, Chang W-S, Chen H-W. Antiviral efficacy of nanoparticulate vacuolar ATPase inhibitors against influenza virus infection. Int J Nanomed. 2018;13:8579-8593.

    Not in our library10.2147/ijn.s185806

  153. 153.

    Abbott TR, Dhamdhere G, Liu Y, Lin X, Goudy L, Zeng L, et al. Development of CRISPR as an antiviral strategy to combat SARS-CoV-2 and influenza. Cell. 2020;181(865–876):e12.

    Not in our library10.1016/j.cell.2020.04.020

  154. 154.

    Baram-Pinto D, Shukla S, Gedanken A, Sarid R. Inhibition of HSV-1 attachment, entry, and cell-to-cell spread by functionalized multivalent gold nanoparticles. Small. 2010;6:1044-1050.

    Not in our library10.1002/smll.200902384

  155. 155.
  156. 156.

    Cagno V, Andreozzi P, D’Alicarnasso M, Jacob Silva P, Mueller M, Galloux M, et al. Broad-spectrum non-toxic antiviral nanoparticles with a virucidal inhibition mechanism. Nat Mater. 2018;17:195-203.

    Not in our library10.1038/nmat5053

  157. 157.

    Jones ST, Cagno V, Janeček M, Ortiz D, Gasilova N, Piret J, et al. Modified cyclodextrins as broad-spectrum antivirals. Sci Adv. 2020;6:eaax9318.

    Not in our library10.1126/sciadv.aax9318

  158. 158.

    Wu C-J, Huang H-W, Liu C-Y, Hong C-F, Chan Y-L. Inhibition of SARS-CoV replication by siRNA. Antiviral Res. 2005;65:45-48.

    Not in our library10.1016/j.antiviral.2004.09.005

  159. 159.

    Li T, Zhang Y, Fu L, Yu C, Li X, Li Y, et al. siRNA targeting the Leader sequence of SARS-CoV inhibits virus replication. Gene Ther. 2005;12:751-761.

    Not in our library10.1038/sj.gt.3302479

  160. 160.

    Rabaan AA, Al-Ahmed SH, Haque S, Sah R, Tiwari R, Malik YS, et al. SARS-CoV-2, SARS-CoV, and MERS-COV: a comparative overview. Infez Med. 2020;28:174-184.

    Not in our library

  161. 161.

    Ceccarelli M, Berretta M, Venanzi Rullo E, Nunnari G, Cacopardo B. Differences and similarities between Severe Acute Respiratory Syndrome (SARS)-CoronaVirus (CoV) and SARS-CoV-2. Would a rose by another name smell as sweet? Eur Rev Med Pharmacol Sci. 2020;24:2781-2783.

    Not in our library10.26355/eurrev_202003_20551

  162. 162.

    Ghosh S, Firdous SM, Nath A. siRNA could be a potential therapy for COVID-19. EXCLI J. 2020;19:528-531.

    Not in our library10.17179/excli2020-1328

  163. 163.

    Levanova A, Poranen MM. RNA interference as a prospective tool for the control of human viral infections. Front Microbiol. 2018;9:2151.

    Not in our library10.3389/fmicb.2018.02151

  164. 164.

    Rohiwal SS, Dvorakova N, Klima J, Vaskovicova M, Senigl F, Slouf M, et al. Polyethylenimine based magnetic nanoparticles mediated non-viral CRISPR/Cas9 system for genome editing. Sci Rep. 2020;10:4619.

    Not in our library10.1038/s41598-020-61465-6

  165. 165.
  166. 166.

    Tanaka P, Santos J, Oliveira E, Miglioli N, Assis A, Monteleone-Cassiano A, et al. A Crispr-Cas9 system designed to introduce point mutations into the human ACE2 gene to weaken the interaction of the ACE2 receptor with the SARS-CoV-2 S protein. Preprints; 2020. https://www.preprints.org/manuscript/202005.0134/v1. Accessed 19 June 2020.

    Not in our library

  167. 167.

    Deng H, Huang W, Zhang Z. Nanotechnology based CRISPR/Cas9 system delivery for genome editing: progress and prospect. Nano Res. 2019;12:2437-2450.

    Not in our library

  168. 168.

    Aghamiri S, Talaei S, Ghavidel AA, Zandsalimi F, Masoumi S, Hafshejani NH, et al. Nanoparticles-mediated CRISPR/Cas9 delivery: recent advances in cancer treatment. J Drug Deliv Sci Technol. 2020;56:101533.

    Not in our library

  169. 169.

    Glass Z, Li Y, Xu Q. Nanoparticles for CRISPR–Cas9 delivery. Nat Biomed Eng. 2017;1:854-855.

    Not in our library10.1038/s41551-017-0158-x

  170. 170.

    Lee K, Conboy M, Park HM, Jiang F, Kim HJ, Dewitt MA, et al. Nanoparticle delivery of Cas9 ribonucleoprotein and donor DNA in vivo induces homology-directed DNA repair. Nat Biomed Eng. 2017;1:889-901.

    Not in our library10.1038/s41551-017-0137-2

  171. 171.

    Chen F, Alphonse M, Liu Q. Strategies for nonviral nanoparticle-based delivery of CRISPR/Cas9 therapeutics. WIREs Nanomed Nanobiotechnol. 2020;12:e1609.

    Not in our library10.1002/wnan.1609

  172. 172.

    Liu J, Chang J, Jiang Y, Meng X, Sun T, Mao L, et al. Fast and efficient CRISPR/Cas9 genome editing in vivo enabled by bioreducible lipid and messenger RNA nanoparticles. Adv Mater. 2019;31:1902575.

    Not in our library10.1002/adma.201902575

  173. 173.

    Moyer TJ, Zmolek AC, Irvine DJ. Beyond antigens and adjuvants: formulating future vaccines. J Clin Investig. 2016;126:799.

    Not in our library10.1172/jci81083

  174. 174.

    Sautto GA, Kirchenbaum GA, Diotti RA, Criscuolo E, Ferrara F. Next generation vaccines for infectious diseases. J Immunol Res. 2019;2019:5890962.

    Not in our library10.1155/2019/5890962

  175. 175.

    Lung P, Yang J, Li Q. Nanoparticle formulated vaccines: opportunities and challenges. Nanoscale. 2020;12:5746-5763.

    Not in our library10.1039/c9nr08958f

  176. 176.

    Kim S-H, Jang Y-S. The development of mucosal vaccines for both mucosal and systemic immune induction and the roles played by adjuvants. Clin Exp Vaccine Res. 2017;6:15.

    Not in our library10.7774/cevr.2017.6.1.15

  177. 177.
  178. 178.

    Kim CG, Kye Y-C, Yun C-H. The role of nanovaccine in cross-presentation of antigen-presenting cells for the activation of CD8+ T cell responses. Pharmaceutics. 2019;11:612.

    Not in our library10.3390/pharmaceutics11110612

  179. 179.

    Xiang SD, Scholzen A, Minigo G, David C, Apostolopoulos V, Mottram PL, et al. Pathogen recognition and development of particulate vaccines: does size matter? Methods. 2006;40:1-9.

    Not in our library10.1016/j.ymeth.2006.05.016

  180. 180.

    Shin MD, Shukla S, Chung YH, Beiss V, Chan SK, Ortega-Rivera OA, et al. COVID-19 vaccine development and a potential nanomaterial path forward. Nat Nanotechnol. 2020;15:646-655.

    Not in our library10.1038/s41565-020-0737-y

  181. 181.
  182. 182.

    Moon JJ, Suh H, Polhemus ME, Ockenhouse CF, Yadava A, Irvine DJ. Antigen-displaying lipid-enveloped PLGA nanoparticles as delivery agents for a Plasmodium vivax malaria vaccine. PLoS ONE. 2012;7:e31472.

    Not in our library10.1371/journal.pone.0031472

  183. 183.

    Papadopoulos NG, Megremis S, Kitsioulis NA, Vangelatou O, West P, Xepapadaki P. Promising approaches for the treatment and prevention of viral respiratory illnesses. J Allergy Clin Immunol. 2017;140:921-932.

    Not in our library10.1016/j.jaci.2017.07.001

  184. 184.

    Gomes AC, Mohsen M, Bachmann MF. Harnessing nanoparticles for immunomodulation and vaccines. Vaccines. 2017;5:6.

    Not in our library10.3390/vaccines5010006

  185. 185.

    Angioletti-Uberti S. Theory, simulations and the design of functionalized nanoparticles for biomedical applications: a soft matter perspective. npj Comput Mater. 2017;3:48.

    Not in our library

  186. 186.

    Schneider CS, Xu Q, Boylan NJ, Chisholm J, Tang BC, Schuster BS, et al. Nanoparticles that do not adhere to mucus provide uniform and long-lasting drug delivery to airways following inhalation. Sci Adv. 2017;3:e1601556.

    Not in our library10.1126/sciadv.1601556

  187. 187.

    Lurie N, Saville M, Hatchett R, Halton J. Developing covid-19 Vaccines At Pandemic Speed. N Engl J Med. 2020;382:1969-1973.

    Not in our library10.1056/nejmp2005630

  188. 188.

    Amanat F, Krammer F. SARS-CoV-2 vaccines: status report. Immunity. 2020;52:583-589.

    Not in our library10.1016/j.immuni.2020.03.007

  189. 189.

    Du L, He Y, Zhou Y, Liu S, Zheng B-J, Jiang S. The spike protein of SARS-CoV—a target for vaccine and therapeutic development. Nat Rev Microbiol. 2009;7:226-236.

    Not in our library10.1038/nrmicro2090

  190. 190.
  191. 191.

    EpiVax. EPV-CoV19: HCW vaccine. EpiVax, Inc.—Informatics and Immunology. 2020. https://epivax.com/pipeline/epv-cov19. Accessed 16 June 2020.

    Not in our library

  192. 192.

    Magnusson SE, Altenburg AF, Bengtsson KL, Bosman F, de Vries RD, Rimmelzwaan GF, et al. Matrix-M™ adjuvant enhances immunogenicity of both protein- and modified vaccinia virus Ankara-based influenza vaccines in mice. Immunol Res. 2018;66:224-233.

    Not in our library10.1007/s12026-018-8991-x

  193. 193.

    Novavax. Novavax to receive up to $388 million funding from CEPI for COVID-19 vaccine development and manufacturing | Novavax Inc. - IR Site. 2020. http://ir.novavax.com/news-releases/news-release-details/novavax-receive-388-million-funding-cepi-covid-19-vaccine. Accessed 16 June 2020.

    Not in our library

  194. 194.
  195. 195.

    Pardi N, Hogan MJ, Porter FW, Weissman D. mRNA vaccines—a new era in vaccinology. Nat Rev Drug Discov. 2018;17:261-279.

    Not in our library10.1038/nrd.2017.243

  196. 196.

    WHO. Draft landscape of COVID-19 candidate vaccines. 2020. https://www.who.int/who-documents-detail-redirect/draft-landscape-of-covid-19-candidate-vaccines. Accessed 13 June 2020.

    Not in our library

  197. 197.

    Sportelli MC, Picca RA, Cioffi N. Recent advances in the synthesis and characterization of nano-antimicrobials. Trends Anal Chem. 2016;84:131-138.

    Not in our library

  198. 198.

    Gunell M, Haapanen J, Brobbey KJ, Saarinen JJ, Toivakka M, Mäkelä JM, et al. Antimicrobial characterization of silver nanoparticle-coated surfaces by “touch test” method. Nanotechnol Sci Appl. 2017;10:137-145.

    Not in our library10.2147/nsa.s139505

  199. 199.

    Swaminathan M, Sharma NK. Antimicrobial Activity of the engineered nanoparticles used as coating agents. In: Martínez LMT, Kharissova OV, Kharisov BI, editors. Handbook of ecomaterials. Cham: Springer International Publishing; 2019. p. 549–63. 10.1007/978-3-319-68255-6_1. Accessed 28 Apr 2020.

    Not in our library

  200. 200.

    Mitchell SL, Carlson EE. Tiny things with enormous impact: nanotechnology in the fight against infectious disease. ACS Infect Dis. 2018;4:1432-1435.

    Not in our library10.1021/acsinfecdis.8b00138

  201. 201.

    Polyak B, Cordovez B. How can we predict behavior of nanoparticles in vivo ? Nanomedicine. 2016;11:189-192.

    Not in our library10.2217/nnm.15.192

  202. 202.
  203. 203.

    Wacker MG, Proykova A, Santos GML. Dealing with nanosafety around the globe-regulation vs. innovation. Int J Pharm. 2016;509:95-106.

    Not in our library10.1016/j.ijpharm.2016.05.015

  204. 204.

    Ventola CL. Progress in nanomedicine: approved and investigational nanodrugs. Pharm Ther. 2017;42:742-755.

    Not in our library

  205. 205.

    Caster JM, Patel AN, Zhang T, Wang A. Investigational nanomedicines in 2016: a review of nanotherapeutics currently undergoing clinical trials. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2017;9:e1416.

    Not in our library10.1002/wnan.1416

  206. 206.

    Zhdanov VP. Formation of a protein corona around nanoparticles. Curr Opin Colloid Interface Sci. 2019;41:95-103.

    Not in our library

  207. 207.

    Lane LA, Qian X, Smith AM, Nie S. Physical chemistry of nanomedicine: understanding the complex behaviors of nanoparticles in vivo. Annu Rev Phys Chem. 2015;66:521-547.

    Not in our library10.1146/annurev-physchem-040513-103718

  208. 208.

    Berrecoso G, Crecente-Campo J, Alonso MJ. Unveiling the pitfalls of the protein corona of polymeric drug nanocarriers. Drug Deliv Transl Res. 2020;10:730-750.

    Not in our library10.1007/s13346-020-00745-0

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