Primary HIV-1 Infection Sets the Stage for Important B Lymphocyte Dysfunctions
Grutzmeier Sven, Tambussi Giuseppe, Tassandin Chiara and 8 more
Retrovirology · 2005
doi:10.1186/1742-4690-2-s1-p95 (opens in a new tab)
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Abstract
Design and Methods B cells of 31 PHI patients (sampled at baseline, 1 month and 6 months post therapy), 26 CHI patients, and 12 healthy donors were studied for surface expression of Fas, LAIR-1, CD70, intracellular expression of Bcl-2, and spontaneous apoptosis. Four-colour FACS (IgD+IgM+CD19+CD27), and short-term PBMC cultures to analyse induction of CD25 on B cells were performed in 5 PHI patients.
Abstract licence: CC BY-NC-ND
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