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Modulation of oxidative stress and TNFα secretion by peritoneal macrophages of arthritic rats fed with a flavonoid-enriched diet

Franch A, Castellote C, Ramírez-Santana C and 3 more

Journal of Translational Medicine · 2010

doi:10.1186/1479-5876-8-s1-p24 (opens in a new tab)

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Abstract

The inflammatory response increases the oxidative stress and cytokine production, such as TNFα, in macrophages. Flavonoids, present in vegetables, have potential antioxidant and anti-inflammatory properties. Previous studies have shown that a flavonoid-enriched cocoa extract added to macrophages in vitro decreases the secretion of NO and TNFα [ 1 ].

Abstract licence: CC BY-NC-ND

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