How long do nosocomial pathogens persist on inanimate surfaces? A systematic review

Abstract

BACKGROUND: Inanimate surfaces have often been described as the source for outbreaks of nosocomial infections. The aim of this review is to summarize data on the persistence of different nosocomial pathogens on inanimate surfaces. METHODS: The literature was systematically reviewed in MedLine without language restrictions. In addition, cited articles in a report were assessed and standard textbooks on the topic were reviewed. All reports with experimental evidence on the duration of persistence of a nosocomial pathogen on any type of surface were included. RESULTS: Most gram-positive bacteria, such as Enterococcus spp. (including VRE), Staphylococcus aureus (including MRSA), or Streptococcus pyogenes, survive for months on dry surfaces. Many gram-negative species, such as Acinetobacter spp., Escherichia coli, Klebsiella spp., Pseudomonas aeruginosa, Serratia marcescens, or Shigella spp., can also survive for months. A few others, such as Bordetella pertussis, Haemophilus influenzae, Proteus vulgaris, or Vibrio cholerae, however, persist only for days. Mycobacteria, including Mycobacterium tuberculosis, and spore-forming bacteria, including Clostridium difficile, can also survive for months on surfaces. Candida albicans as the most important nosocomial fungal pathogen can survive up to 4 months on surfaces. Persistence of other yeasts, such as Torulopsis glabrata, was described to be similar (5 months) or shorter (Candida parapsilosis, 14 days). Most viruses from the respiratory tract, such as corona, coxsackie, influenza, SARS or rhino virus, can persist on surfaces for a few days. Viruses from the gastrointestinal tract, such as astrovirus, HAV, polio- or rota virus, persist for approximately 2 months. Blood-borne viruses, such as HBV or HIV, can persist for more than one week. Herpes viruses, such as CMV or HSV type 1 and 2, have been shown to persist from only a few hours up to 7 days. CONCLUSION: The most common nosocomial pathogens may well survive or persist on surfaces for months and can thereby be a continuous source of transmission if no regular preventive surface disinfection is performed.

References 127

1. 1.

   This reference’s wording can’t be shown under the paper’s licence.

   Not in our library10.1067/mic.2002.127205

2. 2.

   This reference’s wording can’t be shown under the paper’s licence.

   Not in our library10.1016/s0195-6701(01)90017-9

3. 3.

   This reference’s wording can’t be shown under the paper’s licence.

   Not in our library10.1067/mic.2003.49

4. 4.

   This reference’s wording can’t be shown under the paper’s licence.

   Not in our library10.1053/jhin.2002.1279

5. 5.

   This reference’s wording can’t be shown under the paper’s licence.

   Not in our library10.1007/s00103-003-0752-9

6. 6.

   This reference’s wording can’t be shown under the paper’s licence.

   Not in our library

7. 7.

   This reference’s wording can’t be shown under the paper’s licence.

   Not in our library10.1128/cmr.17.4.863-893.2004

8. 8.

   This reference’s wording can’t be shown under the paper’s licence.

   Not in our library10.1128/cmr.14.3.528-546.2001

9. 9.

   This reference’s wording can’t be shown under the paper’s licence.

   Not in our library10.1128/jcm.38.2.724-726.2000

10. 10.

    This reference’s wording can’t be shown under the paper’s licence.

    Not in our library10.1016/s0195-6701(97)90229-2

11. 11.

    This reference’s wording can’t be shown under the paper’s licence.

    Not in our library10.1007/bf01713142

12. 12.

    This reference’s wording can’t be shown under the paper’s licence.

    Not in our library

13. 13.

    This reference’s wording can’t be shown under the paper’s licence.

    Not in our library10.1016/0195-6701(91)90223-u

14. 14.

    This reference’s wording can’t be shown under the paper’s licence.

    Not in our library

15. 15.

    This reference’s wording can’t be shown under the paper’s licence.

    Not in our library10.4315/0362-028x-57.11.963

16. 16.

    This reference’s wording can’t be shown under the paper’s licence.

    Not in our library

17. 17.

    This reference’s wording can’t be shown under the paper’s licence.

    Not in our library10.1111/j.1365-2672.2004.02530.x

18. 18.

    This reference’s wording can’t be shown under the paper’s licence.

    Not in our library10.1128/jcm.34.12.2881-2887.1996

19. 19.

    This reference’s wording can’t be shown under the paper’s licence.

    Not in our library10.1016/s0195-6701(98)90263-8

20. 20.

    This reference’s wording can’t be shown under the paper’s licence.

    Not in our library10.1016/j.jhin.2005.12.008

21. 21.

    This reference’s wording can’t be shown under the paper’s licence.

    Not in our library

22. 22.

    This reference’s wording can’t be shown under the paper’s licence.

    Not in our library10.1016/j.ijfoodmicro.2005.04.021

23. 23.

    This reference’s wording can’t be shown under the paper’s licence.

    Not in our library

24. 24.

    This reference’s wording can’t be shown under the paper’s licence.

    Not in our library

25. 25.

    This reference’s wording can’t be shown under the paper’s licence.

    Not in our library10.1128/jcm.35.6.1394-1397.1997

26. 26.

    This reference’s wording can’t be shown under the paper’s licence.

    Not in our library10.1111/j.1365-2672.1993.tb01589.x

27. 27.

    This reference’s wording can’t be shown under the paper’s licence.

    Not in our library10.1007/bf01969538

28. 28.

    This reference’s wording can’t be shown under the paper’s licence.

    Not in our library10.1097/00004630-200021060-00009

29. 29.

    This reference’s wording can’t be shown under the paper’s licence.

    Not in our library10.1086/503214

30. 30.

    This reference’s wording can’t be shown under the paper’s licence.

    Not in our library

31. 31.

    This reference’s wording can’t be shown under the paper’s licence.

    Not in our library

32. 32.

    This reference’s wording can’t be shown under the paper’s licence.

    Not in our library

33. 33.

    This reference’s wording can’t be shown under the paper’s licence.

    Not in our library10.1139/m87-136

34. 34.

    This reference’s wording can’t be shown under the paper’s licence.

    Not in our library10.1139/m75-121

35. 35.

    This reference’s wording can’t be shown under the paper’s licence.

    Not in our library10.1128/aem.57.5.1394-1399.1991

36. 36.

    This reference’s wording can’t be shown under the paper’s licence.

    Not in our library10.1093/clinids/13.3.448

37. 37.

    This reference’s wording can’t be shown under the paper’s licence.

    Not in our library10.1017/s0022172400066055

38. 38.

    This reference’s wording can’t be shown under the paper’s licence.

    Not in our library10.1128/aem.67.9.3904-3907.2001

39. 39.

    This reference’s wording can’t be shown under the paper’s licence.

    Not in our library

40. 40.

    This reference’s wording can’t be shown under the paper’s licence.

    Not in our library10.1016/s0161-6420(93)31389-8

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