Rosai-dorfman disease of the fibula: A case report
Glen Purnomo, Jesus Adrian A Dueñas, Richard S Rotor and 1 more
Journal of Orthopaedics, Trauma and Rehabilitation · 2019
doi:10.1177/2210491719842950 (opens in a new tab)
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Abstract
Rosai–Dorfman disease (RDD) is usually characterized by painless bilateral cervical lymphadenopathy associated with fever and leukocytosis. Although the disease may occur outside lymphnodes, manifestation of skeletal system occurs in less than 8% of cases. In addition, presentation of this disease in a purely skeletal form without lymph nodes involvement is extremely uncommon. This case report describes a 17-year-old female with a pure skeletal presentation of RDD in the fibula. Trocar biopsy was performed, and immunohistochemical staining using S100 and CD68 was done to confirm the diagnosis.
Abstract licence: CC BY-NC
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