Parathyroid carcinoma: case report
Matheus Henrique de Freitas Silva, Pedro Otávio de Resende Morais, Thaís Andrade de Souza and 4 more
Medicina · 2018
doi:10.11606/issn.2176-7262.v50i6p390-397 (opens in a new tab)
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Abstract
Parathyroid carcinoma (PC) is an uncommon pathology which has propaedeutic and therapeutic peculiarities. In general, it presents as symptomatic primary hyperparathyroidism, that corresponds to only 1% in this subgroup. Both the clinical and histological diagnosis of PC are difficult due to inconsistent criteria. Laboratorial exams commonly present hypercalcemia and PTH well-above the reference value. Surgery is the only curative and effective treatment for parathyroid carcinoma. Case report: Patient M.P.R.L., 48 years old, female, melanodermic, native and from Felisburgo - MG. The disease had been progressing for 2 years with progressive weakness, anemia, renal dysfunction, chronic pain and weight loss (about 15 kg in last five months), associated with PTH-dependent hypercalcemia and renal function decline. A cervical study showed the presence of two thyroid nodules whereas a parathyroid scintigraphy showed no evidence of glands hyperplasia or adenoma. She was admitted to the Santa Casa Hospital of Belo Horizonte for a propaedeutic and therapeutic management of the presented profile.
Abstract licence: CC BY
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