[Retracted] Essential Oils Loaded in Nanosystems: A Developing Strategy for a Successful Therapeutic Approach

Abstract

Essential oils are complex blends of a variety of volatile molecules such as terpenoids, phenol‐derived aromatic components, and aliphatic components having a strong interest in pharmaceutical, sanitary, cosmetic, agricultural, and food industries. Since the middle ages, essential oils have been widely used for bactericidal, virucidal, fungicidal, antiparasitical, insecticidal, and other medicinal properties such as analgesic, sedative, anti‐inflammatory, spasmolytic, and locally anaesthetic remedies. In this review their nanoencapsulation in drug delivery systems has been proposed for their capability of decreasing volatility, improving the stability, water solubility, and efficacy of essential oil‐based formulations, by maintenance of therapeutic efficacy. Two categories of nanocarriers can be proposed: polymeric nanoparticulate formulations, extensively studied with significant improvement of the essential oil antimicrobial activity, and lipid carriers, including liposomes, solid lipid nanoparticles, nanostructured lipid particles, and nano‐ and microemulsions. Furthermore, molecular complexes such as cyclodextrin inclusion complexes also represent a valid strategy to increase water solubility and stability and bioavailability and decrease volatility of essential oils.

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Cited by papers we hold 9

• Essential Oils: Chemistry and Pharmacological Activities · 2023
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• Essential Oils: Pharmaceutical Applications and Encapsulation Strategies into Lipid-Based Delivery Systems · 2021
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• An Overview of Micro- and Nanoemulsions as Vehicles for Essential Oils: Formulation, Preparation and Stability · 2020
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• Nanotechnologies in Food Science: Applications, Recent Trends, and Future Perspectives · 2020
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• Nanoparticles and Controlled Delivery for Bioactive Compounds: Outlining Challenges for New “Smart-Foods” for Health · 2018
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• Anticancer Properties of Essential Oils and Other Natural Products · 2018
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• Nano based drug delivery systems: recent developments and future prospects · 2018
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• Antimicrobial Activity of Some Essential Oils—Present Status and Future Perspectives · 2017
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• Antibacterial Activity of Essential Oils and Their Isolated Constituents against Cariogenic Bacteria: A Systematic Review · 2015
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