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Sex Differences in Drug Disposition

Offie P. Soldin, Sarah H. Chung, Donald R. Mattison

BioMed Research International · 2011 · Review · CC BY

doi:10.1155/2011/187103

Abstract

Physiological, hormonal, and genetic differences between males and females affect the prevalence, incidence, and severity of diseases and responses to therapy. Understanding these differences is important for designing safe and effective treatments. This paper summarizes sex differences that impact drug disposition and includes a general comparison of clinical pharmacology as it applies to men and women.

References 117

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