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Sex Differences in Drug Disposition
Offie P. Soldin, Sarah H. Chung, Donald R. Mattison
BioMed Research International · 2011 · Review · CC BY
Abstract
Physiological, hormonal, and genetic differences between males and females affect the prevalence, incidence, and severity of diseases and responses to therapy. Understanding these differences is important for designing safe and effective treatments. This paper summarizes sex differences that impact drug disposition and includes a general comparison of clinical pharmacology as it applies to men and women.
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