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MicroRNA-like RNA Functions Are Required for the Biosynthesis of Active Compounds in the Medicinal Fungus Sanghuangporus vaninii

Qiumei Zhou, Xuebing Yin, Hanghang Zhang and 1 more

Microbiology Spectrum · 2022

doi:10.1128/spectrum.00219-22 (opens in a new tab)

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Abstract

Fungi can take up environmental RNA that can silence fungal genes with RNA interference, which prompts the development of SIGS. Efficient dsRNA and milRNA uptake in S. vanini , successful dsRNA-targeted gene block, and the increase in intracellular miRNA abundance showed that SIGS technology is an effective and powerful tool for the functional dissection of fungal genes and millRNAs.

Abstract licence: CC BY

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