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Development of a Machine Learning-Based Cysticidal Assay and Identification of an Amebicidal and Cysticidal Marine Microbial Metabolite against Acanthamoeba

Brian Shing, Mina Balen, William Fenical and 1 more

Microbiology Spectrum · 2022

doi:10.1128/spectrum.00077-22 (opens in a new tab)

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Abstract

The free-living Acanthamoeba can exist as a trophozoite or cyst and both stages can cause painful blinding keratitis. Infection recurrence occurs in approximately 10% of cases due to the lack of efficient drugs that can kill both trophozoites and cysts.

Abstract licence: CC BY

References17

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