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Outer Membrane Vesicles Protect Gram-Negative Bacteria against Host Defense Peptides

Melanie D. Balhuizen, Albert van Dijk, Jeroen W. A. Jansen and 3 more

mSphere · 2021

doi:10.1128/msphere.00523-21 (opens in a new tab)

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Abstract

Antibiotic resistance is a pressing problem and estimated to be a leading cause of mortality by 2050. Antimicrobial peptides, also known as host defense peptides (HDPs), and HDP-derived antimicrobials have potent antimicrobial activity and high potential as alternatives to antibiotics due to low resistance development.

Abstract licence: CC BY

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