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A Family of Toxoplasma gondii Genes Related to GRA12 Regulate Cyst Burdens and Cyst Reactivation

Rebekah B. Guevara, Barbara A. Fox, David J. Bzik

mSphere · 2021

doi:10.1128/msphere.00182-21 (opens in a new tab)

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Abstract

If host immunity weakens, Toxoplasma gondii cysts recrudesce in the central nervous system and cause a severe toxoplasmic encephalitis. Current therapies target acute stage infection but do not eliminate chronic cysts.

Abstract licence: CC BY

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