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Intracellular Density of Wolbachia Is Mediated by Host Autophagy and the Bacterial Cytoplasmic Incompatibility Gene cifB in a Cell Type-Dependent Manner in Drosophila melanogaster

Mark Deehan, Weiwei Lin, Benjamin Blum and 2 more

mBio · 2021

doi:10.1128/mbio.02205-20 (opens in a new tab)

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Abstract

Autophagy is a eukaryotic intracellular degradation pathway which can act as an innate immune response to eliminate pathogens. Conversely, pathogens can evolve proteins which modulate the autophagy pathway to subvert degradation and establish an infection. Wolbachia

Abstract licence: CC BY

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