MR1 displays the microbial metabolome driving selective MR1-restricted T cell receptor usage

Abstract

A diverse array of microbial metabolites binds to MR1 and selectively activates MR1-restricted T cells.

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• Antigen Recognition by MR1-Reactive T Cells; MAIT Cells, Metabolites, and Remaining Mysteries · 2020
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• Unbiased Profiling Reveals Compartmentalization of Unconventional T-Cells Within the Intestinal Mucosa Irrespective of HIV Infection · 2020
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