(6R)-2-tert-Butyl-6-[(4R,5S)-3-isopropyl-4-methyl-5-phenyloxazolidin-2-yl]phenol
Takaoki Koyanagi, Kate L. Edler, Raleigh W. Parrott II and 2 more
Acta Crystallographica Section E · 2010
doi:10.1107/s1600536810009591 (opens in a new tab)
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Abstract
In the title compound, C23H31NO2, the lone pair on the nitrogen atom is oriented to facilitate intramolecular hydrogen bonding with the hydroxy group residing on the phenyl substituent. The five-membered ring adopts an envelope confornmation with the O atom at the flap. The absolute stereochemistry was verified by measurement of optical activity using a digital polarimeter.
Abstract licence: CC BY
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