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High-resolution structures of the SARS-CoV-2 2′- O -methyltransferase reveal strategies for structure-based inhibitor design

Monica Rosas-Lemus, George Minasov, Ludmilla Shuvalova and 4 more

Science Signaling · 2020 · CC BY

doi:10.1101/2020.08.03.234716

Abstract

Crystal structures of an mRNA-capping enzyme from SARS-CoV-2 in complex with its substrates suggest targets for drug design.

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