The receptor-binding domain of the viral spike protein is an immunodominant and highly specific target of antibodies in SARS-CoV-2 patients

Abstract

The serum level of RBD-binding antibodies correlates with SARS-CoV-2 neutralization and can be used for population-level surveillance.

Cited by papers we hold 28

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• Persistence of SARS-CoV-2-specific B and T cell responses in convalescent COVID-19 patients 6–8 months after the infection · 2021
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• Immunity, virus evolution, and effectiveness of SARS-CoV-2 vaccines · 2021
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• The Case for S2: The Potential Benefits of the S2 Subunit of the SARS-CoV-2 Spike Protein as an Immunogen in Fighting the COVID-19 Pandemic · 2021
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• A New SARS-CoV-2 Dual-Purpose Serology Test: Highly Accurate Infection Tracing and Neutralizing Antibody Response Detection · 2021
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• Understanding neutralising antibodies against SARS-CoV-2 and their implications in clinical practice · 2021
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• Seven-month kinetics of SARS-CoV-2 antibodies and role of pre-existing antibodies to human coronaviruses · 2021
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• Molecular determinants and mechanism for antibody cocktail preventing SARS-CoV-2 escape · 2021
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• As Plain as the Nose on Your Face: The Case for A Nasal (Mucosal) Route of Vaccine Administration for Covid-19 Disease Prevention · 2020
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• Humoral Responses and Serological Assays in SARS-CoV-2 Infections · 2020
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• Biodistribution and serologic response in SARS-CoV-2 induced ARDS: A cohort study. · 2020
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• The SARS-CoV-2 Spike Glycoprotein Biosynthesis, Structure, Function, and Antigenicity: Implications for the Design of Spike-Based Vaccine Immunogens · 2020
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and 8 more

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