No retraction, correction or concern found when last checked on Nov 2, 2026.
WAO Guideline for the Management of Hereditary Angioedema
Timothy Craig, Emel Aygören Pürsün, Konrad Bork and 15 more
World Allergy Organization Journal · 2012 · CC BY-NC-ND
doi:10.1097/wox.0b013e318279affa
Abstract
: Hereditary Angioedema (HAE) is a rare disease and for this reason proper diagnosis and appropriate therapy are often unknown or not available for physicians and other health care providers. For this reason we convened a group of specialists that focus upon HAE from around the world to develop not only a consensus on diagnosis and management of HAE, but to also provide evidence based grades, strength of evidence and classification for the consensus. Since both consensus and evidence grading were adhered to the document meets criteria as a guideline. The outcome of the guideline is to improve diagnosis and management of patients with HAE throughout the world and to help initiate uniform care and availability of therapies to all with the diagnosis no matter where the residence of the individual with HAE exists.
Shown for reading. Its publisher allows quoting it, not republishing it.
References 141
- 1.
Brozek JL Akl EA Alonso-Coello P Lang D Jaeschke R Grading quality of evidence and strength of recommendations in clinical practice guidelines. Part 1 of 3. An overview of the GRADE approach and grading quality of evidence about interventionsAllergy2009 5669677
Not in our library10.1111/j.1398-9995.2009.01973.x
- 2.
Cicardi M Bork K Caballero T Craig T Li HH Longhurst H Reshef A Zuraw B Evidence-based recommendations for the therapeutic management of angioedema owing to hereditary C1 inhibitor deficiency: consensus report of an International Working GroupAllergy2012 5147157
Not in our library10.1111/j.1398-9995.2011.02751.x
- 3.
Munch EP Weeke B Non-hereditary angioedema treated with tranexamic acid. A 6-month placebo controlled trial with follow-up 4 years laterAllergy1985 59297
Not in our library10.1111/j.1398-9995.1985.tb02666.x
- 4.
Lewis JH Idiopathic gastric acid hypersecretion: treatment implications for refractory acid/peptic disordersAliment Pharmacol Ther1991 5suppl 11524
Not in our library10.1111/j.1365-2036.1991.tb00745.x
- 5.
Gluszko P Undas A Amenta S Szczeklik A Schmaier AH Administration of gamma interferon in human subjects decreases plasminogen activation and fibrinolysis without influencing C1 inhibitorJ Lab Clin Med1994 5232240
Not in our library
- 6.
Cicardi M Mannucci PM Castelli R Rumi MG Agostoni A Reduction in transmission of hepatitis C after the introduction of a heat-treatment step in the production of C1-inhibitor concentrateTransfusion1995 5209212
Not in our library10.1046/j.1537-2995.1995.35395184276.x
- 7.
Waytes AT Rosen FS Frank MM Treatment of hereditary angioedema with a vapor-heated C1 inhibitor concentrateN Engl J Med1996 516301634
Not in our library10.1056/nejm199606203342503
- 8.
Cicardi M Castelli R Zingale LC Agostoni A Side effects of long-term prophylaxis with attenuated androgens in hereditary angioedema: comparison of treated and untreated patientsJ Allergy Clin Immunol1997 5194196
Not in our library10.1016/s0091-6749(97)70095-2
- 9.
Goring HD Bork K Späth PJ Bauer R Ziemer A Hintner H Wüthrich B Hereditary angioedema in the German-speaking region [in German]Hautarzt1998 5114122
Not in our library10.1007/s001050050710
- 10.
Kunschak M Engl W Maritsch F Rosen FS Eder G Zerlauth G Schwarz HP A randomized, controlled trial to study the efficacy and safety of C1 inhibitor concentrate in treating hereditary angioedemaTransfusion1998 5540549
Not in our library10.1046/j.1537-2995.1998.38698326333.x
- 11.
Farkas H Gyeney L Gidófalvy E Füst G Varga L The efficacy of short-term danazol prophylaxis in hereditary angioedema patients undergoing maxillofacial and dental proceduresJ Oral Maxillofac Surg1999 5404408
Not in our library10.1016/s0278-2391(99)90280-x
- 12.
Bork K Barnstedt SE Treatment of 193 episodes of laryngeal edema with C1 inhibitor concentrate in patients with hereditary angioedemaArch Intern Med2001 5714718
Not in our library10.1001/archinte.161.5.714
- 13.
Gompels MM Lock RJ Gidófalvy E Füst G Varga L A multicentre evaluation of the diagnostic efficiency of serological investigations for C1 inhibitor deficiencyJ Clin Pathol2002 5145147
Not in our library10.1136/jcp.55.2.145
- 14.
Weiler JM Quinn SA Woodworth GG Brown DD Layton TA Maves KK Does heparin prophylaxis prevent exacerbations of hereditary angioedema?J Allergy Clin Immunol2002 59951000
Not in our library10.1067/mai.2002.124892
- 15.
Szeplaki G Varga L Valentin S Kleiber M Karádi I Adverse effects of danazol prophylaxis on the lipid profiles of patients with hereditary angioedemaJ Allergy Clin Immunol2005 5864869
Not in our library10.1016/j.jaci.2004.12.1130
- 16.
van Doorn MB Burggraaf J van Dam T Eerenberg A Levi M A phase I study of recombinant human C1 inhibitor in asymptomatic patients with hereditary angioedemaJ Allergy Clin Immunol2005 5876883
Not in our library10.1016/j.jaci.2005.05.019
- 17.
Bas M Bier H Greve J Kojda G Hoffmann TK Novel pharmacotherapy of acute hereditary angioedema with bradykinin B2-receptor antagonist icatibantAllergy2006 514901492
Not in our library10.1111/j.1398-9995.2006.01197.x
- 18.
Bork K Frank J Grundt B Schlattmann P Nussberger J Kreuz W Treatment of acute edema attacks in hereditary angioedema with a bradykinin receptor-2 antagonist (Icatibant)J Allergy Clin Immunol2007 514971503
Not in our library10.1016/j.jaci.2007.02.012
- 19.
Ott HW Mattle V Hadziomerovic D Licht P Döinghaus K Treatment of hereditary angioneurotic oedema (HANE) with tiboloneClin Endocrinol (Oxf)2007 5180184
Not in our library10.1111/j.1365-2265.2006.02704.x
- 20.
Schneider L Lumry W Vegh A Williams AH Schmalbach T Critical role of kallikrein in hereditary angioedema pathogenesis: a clinical trial of ecallantide, a novel kallikrein inhibitorJ Allergy Clin Immunol2007 5416422
Not in our library10.1016/j.jaci.2007.04.028
- 21.
Varga L Biro A Széplaki G Tóth L Horváth A Füst G Farkas H Anti-cholesterol antibody levels in hereditary angioedemaJ Cell Mol Med2007 513771383
Not in our library10.1111/j.1582-4934.2007.00124.x
- 22.
Visy B Fust G Bygum A Bork K Longhurst H Helicobacter pylori infection as a triggering factor of attacks in patients with hereditary angioedemaHelicobacter2007 5251257
Not in our library10.1111/j.1523-5378.2007.00501.x
- 23.
Birjmohun RS Kees Hovingh G Stroes ES Hofstra JJ Dallinga-Thie GM Effects of short-term and long-term danazol treatment on lipoproteins, coagulation, and progression of atherosclerosis: two clinical trials in healthy volunteers and patients with hereditary angioedemaClin Ther2008 523142323
Not in our library10.1016/j.clinthera.2008.12.021
- 24.
Cedzynski M Madalinski K Gregorek H Swierzko AS Nowicka E Possible disease-modifying factors: the mannan-binding lectin pathway and infections in hereditary angioedema of children and adultsArch Immunol Ther Exp (Warsz)2008 56975
Not in our library10.1007/s00005-008-0004-7
- 25.
Szegedi R Szeplaki G Varga L Prohászka Z Széplaki Z Long-term danazol prophylaxis does not lead to increased carotid intima-media thickness in hereditary angioedema patientsAtherosclerosis2008 5184191
Not in our library10.1016/j.atherosclerosis.2007.09.025
- 26.
Craig TJ Levy RJ Wasserman RL Bewtra AK Hurewitz D Efficacy of human C1 esterase inhibitor concentrate compared with placebo in acute hereditary angioedema attacksJ Allergy Clin Immunol2009 5801808
Not in our library10.1016/j.jaci.2009.07.017
- 27.
Kreuz W Martinez-Saguer I Aygören-Pürsün E Rusicke E Heller C Klingebiel T C1-inhibitor concentrate for individual replacement therapy in patients with severe hereditary angioedema refractory to danazol prophylaxisTransfusion2009 519871995
Not in our library10.1111/j.1537-2995.2009.02230.x
- 28.
Bas M Greve J Stelter K Bier H Stark T Hoffmann TK Kojda G Therapeutic efficacy of icatibant in angioedema induced by angiotensin-converting enzyme inhibitors: a case seriesAnn Emerg Med2010 5278282
Not in our library10.1016/j.annemergmed.2010.03.032
- 29.
Bernstein JA Ritchie B Levy RJ Wasserman RL Bewtra AK Population pharmacokinetics of plasma-derived C1 esterase inhibitor concentrate used to treat acute hereditary angioedema attacksAnn Allergy Asthma Immunol2010 5149154
Not in our library10.1016/j.anai.2010.06.005
- 30.
Cicardi M Banerji A Bracho F Malbrán A Rosenkranz B Icatibant, a new bradykinin-receptor antagonist, in hereditary angioedemaN Engl J Med2010 5532541
Not in our library10.1056/nejmoa0906393
- 31.
Cicardi M Levy RJ McNeil DL Li HH Sheffer AL Ecallantide for the treatment of acute attacks in hereditary angioedemaN Engl J Med2010 5523531
Not in our library10.1056/nejmoa0905079
- 32.
Craig TJ Wasserman RL Levy RJ Bewtra AK Schneider L Prospective study of rapid relief provided by C1 esterase inhibitor in emergency treatment of acute laryngeal attacks in hereditary angioedemaJ Clin Immunol2010 5823829
Not in our library10.1007/s10875-010-9442-1
- 33.
Levy RJ Lumry WR McNeil DL Li HH Campion M Horn PT Pullman WE EDEMA4: a phase 3, double-blind study of subcutaneous ecallantide treatment for acute attacks of hereditary angioedemaAnn Allergy Asthma Immunol2010 5523529
Not in our library10.1016/j.anai.2010.04.012
- 34.
Zuraw B Cicardi M Levy RJ Nuijens JH Relan A Recombinant human C1-inhibitor for the treatment of acute angioedema attacks in patients with hereditary angioedemaJ Allergy Clin Immunol2010 5821827.e814
Not in our library10.1016/j.jaci.2010.07.021
- 35.
Zuraw BL Busse PJ White M Jacobs J Lumry W Nanofiltered C1 inhibitor concentrate for treatment of hereditary angioedemaN Engl J Med2010 5513522
Not in our library10.1056/nejmoa0805538
- 36.
Bissler JJ Donaldson VH Davis AE Contiguous deletion and duplication mutations resulting in type 1 hereditary angioneurotic edemaHum Genet1994 5265269
Not in our library10.1007/bf00212020
- 37.
Zhang Y Dipple KM Vilain E Huang BL Finlayson G AluY insertion (IVS4-52ins316alu) in the glycerol kinase gene from an individual with benign glycerol kinase deficiencyHum Mutat2000 5316323
Not in our library10.1002/(sici)1098-1004(200004)15:4<316::aid-humu3>3.0.co;2-9
- 38.
Bowen T Hebert J Ritchie B Burnham J MacSween M Management of hereditary angioedema: a Canadian approachTransfus Apher Sci2003 5205214
Not in our library10.1016/j.transci.2003.08.009
- 39.
Bowen T Cicardi M Farkas H Bork K Kreuz W Canadian 2003 International Consensus Algorithm For the Diagnosis, Therapy, and Management of Hereditary AngioedemaJ Allergy Clin Immunol2004 5629637
Not in our library10.1016/j.jaci.2004.06.043
- 40.
Bracho FA Hereditary angioedemaCurr Opin Hematol2005 5493498
Not in our library10.1097/01.moo.0000179805.57486.4e
- 41.
Chinen J Shearer WT Basic and clinical immunologyJ Allergy Clin Immunol2005 5411418
Not in our library10.1016/j.jaci.2005.05.010
- 42.
Gompels MM Lock RJ Abinun M Bethune CA Davies G C1 inhibitor deficiency: consensus documentClin Exp Immunol2005 5379394
Not in our library10.1111/j.1365-2249.2005.02726.x
- 43.
Bowen T Cicardi M Bork K Zuraw B Frank M Hereditary angiodema: a current state-of-the-art review, VII: Canadian Hungarian 2007 International Consensus Algorithm for the Diagnosis, Therapy, and Management of Hereditary AngioedemaAnn Allergy Asthma Immunol2008 5suppl 2S30S40
Not in our library10.1016/s1081-1206(10)60584-4
- 44.
Bowen T Hereditary angioedema consensus 2010Allergy Asthma Clin Immunol2010 513
Not in our library10.1186/1710-1492-6-13
- 45.
- 46.
- 47.
- 48.
Dinkelacker E Ueber acutes Oedem [dissertation]1882 Kiel, Germany: Unversity of Kiel
Not in our library
- 49.
Rosen FS Austen KF The "neurotic edema" (hereditary angioedema)N Engl J Med1969 513561357
Not in our library10.1056/nejm196906122802414
- 50.
Cicardi M Bergamaschini L Marasini B Boccassini G Tucci A Agostoni A Hereditary angioedema: an appraisal of 104 casesAm J Med Sci1982 529
Not in our library10.1097/00000441-198207000-00001
- 51.
Bork K Meng G Staubach P Hardt J Hereditary angioedema: new findings concerning symptoms, affected organs, and courseAm J Med2006 5267274
Not in our library10.1016/j.amjmed.2005.09.064
- 52.
Longhurst HJ Bork K Hereditary angioedema: causes, manifestations and treatmentBr J Hosp Med (Lond)2006 5654657
Not in our library10.12968/hmed.2006.67.12.22439
- 53.
Kaplan AP Greaves MW AngioedemaJ Am Acad Dermatol2005 5373388quiz 389-392
Not in our library10.1016/j.jaad.2004.09.032
- 54.
Seidman MD Lewandowski CA Sarpa JR Potesta E Schweitzer VG Angioedema related to angiotensin-converting enzyme inhibitorsOtolaryngol Head Neck Surg1990 5727731
Not in our library10.1177/019459989010200617
- 55.
Nussberger J Cugno M Amstutz C Cicardi M Pellacani A Agostoni A Plasma bradykinin in angio-oedemaLancet1998 516931697
Not in our library10.1016/s0140-6736(97)09137-x
- 56.
Agostoni A Cicardi M Cugno M Zingale LC Gioffré D Nussberger J Angioedema due to angiotensin-converting enzyme inhibitorsImmunopharmacology1999 52125
Not in our library10.1016/s0162-3109(99)00107-1
- 57.
Rosen FS Pensky J Donaldson V Charache P Hereditary angioneurotic edema: two genetic variantsScience1965 5957958
Not in our library10.1126/science.148.3672.957
- 58.
Roche O Blanch A Caballero T Sastre N Callejo D López-Trascasa M Hereditary angioedema due to C1 inhibitor deficiency: patient registry and approach to the prevalence in SpainAnn Allergy Asthma Immunol2005 5498503
Not in our library10.1016/s1081-1206(10)61121-0
- 59.
Bygum A Hereditary angio-oedema in Denmark: a nationwide surveyBr J Dermatol2009 511531158
Not in our library10.1111/j.1365-2133.2009.09366.x
- 60.
Donaldson VH Rosen FS Action of complement in hereditary angioneurotic edema: the role of C'1-esteraseJ Clin Invest1964 522042213
Not in our library10.1172/jci105094
- 61.
Donaldson VH Rosen FS Bing DH Kinin generation in hereditary angioneurotic edema (H.A.N.E.) plasmaAdv Exp Med Biol1983 5183191
Not in our library
- 62.
Kaplan AP Joseph K Silverberg M Pathways for bradykinin formation and inflammatory diseaseJ Allergy Clin Immunol2002 5195209
Not in our library10.1067/mai.2002.121316
- 63.
Donaldson VH Kinin formation in hereditary angioneurotic edema (HANE) plasmaInt Arch Allergy Appl Immunol1973 5206209
Not in our library10.1159/000231029
- 64.
Fields T Ghebrehiwet B Kaplan AP Kinin formation in hereditary angioedema plasma: evidence against kinin derivation from C2 and in support of "spontaneous" formation of bradykininJ Allergy Clin Immunol1983 55460
Not in our library10.1016/0091-6749(83)90052-0
- 65.
Maurer M Bader M Bas M Bossi F Cicardi M New topics in bradykinin researchAllergy2011 513971406
Not in our library10.1111/j.1398-9995.2011.02686.x
- 66.
Binkley KE Davis A III Clinical, biochemical, and genetic characterization of a novel estrogen-dependent inherited form of angioedemaJ Allergy Clin Immunol2000 5546550
Not in our library10.1067/mai.2000.108106
- 67.
Bork K Barnstedt SE Koch P Traupe H Hereditary angioedema with normal C1-inhibitor activity in womenLancet2000 5213217
Not in our library10.1016/s0140-6736(00)02483-1
- 68.
Bork K Gul D Dewald G Hereditary angio-oedema with normal C1 inhibitor in a family with affected women and menBr J Dermatol2006 5542545
Not in our library10.1111/j.1365-2133.2005.07048.x
- 69.
Caballero T Baeza ML Cabañas R Campos A Cimbollek S Consensus statement on the diagnosis, management, and treatment of angioedema mediated by bradykinin. Part I. Classification, epidemiology, pathophysiology, genetics, clinical symptoms, and diagnosisJ Investig Allergol Clin Immunol2011 5333347quiz follow 347
Not in our library
- 70.
Karim Y Griffiths H Deacock S Normal complement C4 values do not exclude hereditary angioedemaJ Clin Pathol2004 5213214
Not in our library10.1136/jcp.2003.12021
- 71.
Tarzi MD Hickey A Förster T Mohammadi M Longhurst HJ An evaluation of tests used for the diagnosis and monitoring of C1 inhibitor deficiency: normal serum C4 does not exclude hereditary angio-oedemaClin Exp Immunol2007 5513516
Not in our library10.1111/j.1365-2249.2007.03438.x
- 72.
Wagenaar-Bos IG Drouet C Aygören-Pursun E Bork K Bucher C Functional C1-inhibitor diagnostics in hereditary angioedema: assay evaluation and recommendationsJ Immunol Methods2008 51420
Not in our library10.1016/j.jim.2008.06.004
- 73.
Zuraw BL Diagnosis and management of hereditary angioedema: an American approachTransfus Apher Sci2003 5239245
Not in our library10.1016/j.transci.2003.08.008
- 74.
Bork K Hereditary angioedema with normal C1 inhibitor activity including hereditary angioedema with coagulation factor XII gene mutationsImmunol Allergy Clin North Am2006 5709724
Not in our library10.1016/j.iac.2006.09.003
- 75.
Weiler CR van Dellen RG Genetic test indications and interpretations in patients with hereditary angioedemaMayo Clin Proc2006 5958972
Not in our library10.4065/81.7.958
- 76.
Caballero T Baeza ML Cabañas R Campos A Cimbollek S Consensus statement on the diagnosis, management, and treatment of angioedema mediated by bradykinin. Part II. Treatment, follow-up, and special situationsJ Investig Allergol Clin Immunol2011 5422441quiz 442-423
Not in our library
- 77.
Temino VM Peebles RS Jr The spectrum and treatment of angioedemaAm J Med2008 5282286
Not in our library10.1016/j.amjmed.2007.09.024
- 78.
Zuberbier T Asero R Bindslev-Jensen C Walter Canonica G Church MK EAACI/GA(2)LEN/EDF/WAO guideline: management of urticariaAllergy2009 514271443
Not in our library10.1111/j.1398-9995.2009.02178.x
- 79.
Bork K Wulff K Hardt J Witzke G Staubach P Hereditary angioedema caused by missense mutations in the factor XII gene: clinical features, trigger factors, and therapyJ Allergy Clin Immunol2009 5129134
Not in our library10.1016/j.jaci.2009.03.038
- 80.
Farkas H Szongoth M Kaposi PN Karádi I Fekete B Angiooedema due to acquired deficiency of C1-esterase inhibitor associated with leucocytoclastic vasculitisActa Derm Venereol2001 5298300
Not in our library10.1080/00015550152572985
- 81.
Kaplan AP C1 inhibitor deficiency: hereditary and acquired formsJ Investig Allergol Clin Immunol2001 5211219
Not in our library
- 82.
Cugno M Castelli R Cicardi M Angioedema due to acquired C1inhibitor deficiency: a bridging condition between autoimmunity and lymphoproliferationAutoimmun Rev2008 5156159
Not in our library10.1016/j.autrev.2008.05.003
- 83.
Levi M Choi G Picavet C Hack CE Self-administration of C1-inhibitor concentrate in patients with hereditary or acquired angioedema caused by C1-inhibitor deficiencyJ Allergy Clin Immunol2006 5904908
Not in our library10.1016/j.jaci.2006.01.002
- 84.
Bygum A Andersen KE Mikkelsen CS Self-administration of intravenous C1-inhibitor therapy for hereditary angioedema and associated quality of life benefitsEur J Dermatol2009 5147151
Not in our library10.1684/ejd.2008.0603
- 85.
Gras J Icatibant for hereditary angioedemaDrugs Today (Barc)2009 5855864
Not in our library10.1358/dot.2009.45.12.1424267
- 86.
Bork K Recurrent angioedema and the threat of asphyxiationDtsch Arztebl Int2010 5408414
Not in our library10.3238/arztebl.2010.0408
- 87.
Martinez-Saguer I Rusicke E Aygören-Pürsün E Heller C Klingebiel T Kreuz W Characterization of acute hereditary angioedema attacks during pregnancy and breast-feeding and their treatment with C1 inhibitor concentrateAm J Obstet Gynecol2010 5131e1-e7
Not in our library10.1016/j.ajog.2010.03.003
- 88.
Groner A Nowak T Schäfer W Pathogen safety of human C1 esterase inhibitor concentrateTransfusion2012 521042112
Not in our library10.1111/j.1537-2995.2012.03590.x
- 89.
Ärzteschaft A Schwerwiegende Thrombenbildung nach Berinert® HSDeutsches Ärzteblatt2000 5A101623780551
Not in our library
- 90.
Bork K Hardt J Hereditary angioedema: increased number of attacks after frequent treatments with C1 inhibitor concentrateAm J Med2009 5780783
Not in our library10.1016/j.amjmed.2009.02.024
- 91.
Bork K Hardt J Hereditary angioedema: long-term treatment with one or more injections of C1 inhibitor concentrate per weekInt Arch Allergy Immunol2011 58188
Not in our library10.1159/000319213
- 92.
Varga L Farkas H Treatment of type I and II hereditary angioedema with Rhucin, a recombinant human C1 inhibitorExpert Rev Clin Immunol2008 5653661
Not in our library10.1586/1744666x.4.6.653
- 93.
Sheffer AL Campion M Levy RJ Li HH Horn PT Pullman WE Ecallantide (DX-88) for acute hereditary angioedema attacks: integrated analysis of 2 double-blind, phase 3 studiesJ Allergy Clin Immunol2011 5153159.e154
Not in our library10.1016/j.jaci.2011.03.006
- 94.
Bygum A Broesby-Olsen S Rapid resolution of erythema marginatum after icatibant in acquired angioedemaActa Derm Venereol2011 5185186
Not in our library10.2340/00015555-1055
- 95.
Bork K Hardt J Staubach-Renz P Witzke G Risk of laryngeal edema and facial swellings after tooth extraction in patients with hereditary angioedema with and without prophylaxis with C1 inhibitor concentrate: a retrospective studyOral Surg Oral Med Oral Pathol Oral Radiol Endod2011 55864
Not in our library10.1016/j.tripleo.2011.02.034
- 96.
Zuraw BL Hereditary angiodema: a current state-of-the-art review, IV: short-and long-term treatment of hereditary angioedema: out with the old and in with the new?Ann Allergy Asthma Immunol2008 5suppl 2S13S18
Not in our library10.1016/s1081-1206(10)60581-9
- 97.
Maurer M Magerl M Hereditary angioedema: an update on available therapeutic optionsJ Dtsch Dermatol Ges2010 5663672
Not in our library10.1111/j.1610-0387.2010.07450.x
- 98.
Van Sickels NJ Hunsaker RB Van Sickels JE Hereditary angioedema: treatment, management, and precautions in patients presenting for dental careOral Surg Oral Med Oral Pathol Oral Radiol Endod2010 5168172
Not in our library10.1016/j.tripleo.2009.09.031
- 99.
Gompels MM Lock RJ Cinryze (C1-inhibitor) for the treatment of hereditary angioedemaExpert Rev Clin Immunol2011 5569573
Not in our library10.1586/eci.11.50
- 100.
Lunn M Santos C Craig T Cinryze as the first approved C1 inhibitor in the USA for the treatment of hereditary angioedema: approval, efficacy and safetyJ Blood Med2010 5163170
Not in our library10.2147/jbm.s9576
- 101.
Tallroth GA Long-term prophylaxis of hereditary angioedema with a pasteurized C1 inhibitor concentrateInt Arch Allergy Immunol2011 5356359
Not in our library10.1159/000321830
- 102.
Blackmore WP Danazol in the treatment of hereditary angio-neurotic oedemaJ Int Med Res1977 5suppl 33843
Not in our library
- 103.
Agostoni A Cicardi M Martignoni GC Bergamaschini L Marasini B Danazol and stanozolol in long-term prophylactic treatment of hereditary angioedemaJ Allergy Clin Immunol1980 57579
Not in our library10.1016/0091-6749(80)90181-5
- 104.
Wharton JG Hereditary angioedema: response to danazolPractitioner1982 5935936
Not in our library
- 105.
Zurlo JJ Frank MM The long-term safety of danazol in women with hereditary angioedemaFertil Steril1990 56472
Not in our library10.1016/s0015-0282(16)53638-3
- 106.
Cicardi M Bergamaschini L Cugno M Hack E Agostoni G Agostoni A Long-term treatment of hereditary angioedema with attenuated androgens: a survey of a 13-year experienceJ Allergy Clin Immunol1991 5768773
Not in our library10.1016/0091-6749(91)90120-d
- 107.
Bork K Schneiders V Danazol-induced hepatocellular adenoma in patients with hereditary angio-oedemaJ Hepatol2002 5707709
Not in our library10.1016/s0168-8278(02)00035-1
- 108.
Bork K Bygum A Hardt J Benefits and risks of danazol in hereditary angioedema: a long-term survey of 118 patientsAnn Allergy Asthma Immunol2008 5153161
Not in our library10.1016/s1081-1206(10)60424-3
- 109.
Farkas H Czaller I Csuka D Vas A Valentin S The effect of long-term danazol prophylaxis on liver function in hereditary angioedemada longitudinal studyEur J Clin Pharmacol2010 5419426
Not in our library10.1007/s00228-009-0771-z
- 110.
Maurer M Magerl M Long-term prophylaxis of hereditary angioedema with androgen derivates: a critical appraisal and potential alternativesJ Dtsch Dermatol Ges2011 599107
Not in our library10.1111/j.1610-0387.2010.07546.x
- 111.
Sheffer AL Austen KF Rosen FS Tranexamic acid therapy in hereditary angioneurotic edemaN Engl J Med1972 5452454
Not in our library10.1056/nejm197208312870907
- 112.
Crosher R Intravenous tranexamic acid in the management of hereditary angio-oedemaBr J Oral Maxillofac Surg1987 5500506
Not in our library10.1016/0266-4356(87)90143-4
- 113.
Farkas H Harmat G Füst G Varga L Visy B Clinical management of hereditary angio-oedema in childrenPediatr Allergy Immunol2002 5153161
Not in our library10.1034/j.1399-3038.2002.01014.x
- 114.
Caballero T Farkas H Bouillet L Bowen T Gompel A International consensus and practical guidelines on the gynecologic and obstetric management of female patients with hereditary angioedema caused by C1 inhibitor deficiencyJ Allergy Clin Immunol2012 5308320
Not in our library10.1016/j.jaci.2011.11.025
- 115.
Boyle RJ Nikpour M Tang ML Hereditary angio-oedema in children: a management guidelinePediatr Allergy Immunol2005 5288294
Not in our library10.1111/j.1399-3038.2005.00275.x
- 116.
Farkas H Pediatric hereditary angioedema due to C1-inhibitor deficiencyAllergy Asthma Clin Immunol2010 518
Not in our library10.1186/1710-1492-6-18
- 117.
Martinez-Saguer I Rusicke E Aygören-Pürsün E von Hentig N Klingebiel T Kreuz W Pharmacokinetic analysis of human plasma-derived pasteurized C1-inhibitor concentrate in adults and children with hereditary angioedema: a prospective studyTransfusion2010 5354360
Not in our library10.1111/j.1537-2995.2009.02394.x
- 118.
Caballero T Angio-oedema due to hereditary C1 inhibitor deficiency in childrenAllergol Immunopathol (Madr)2012
Not in our library10.1016/j.aller.2012.01.002
- 119.
Kjaer L Bygum A Hereditary angioedema in childhood: a challenging diagnosis you cannot afford to missPediatr Dermatol2012
Not in our library10.1111/j.1525-1470.2011.01675.x
- 120.
Davis CA Vallota EH Forristal J Serum complement levels in infancy: age related changesPediatr Res1979 510431046
Not in our library10.1203/00006450-197909000-00019
- 121.
Roach B Kim Y Jerome E Michael AF Influence of age and sex on serum complement components in childrenAm J Dis Child1981 5918920
Not in our library10.1001/archpedi.1981.02130340030011
- 122.
Nielsen EW Johansen HT Holt J Mollnes TE C1 inhibitor and diagnosis of hereditary angioedema in newbornsPediatr Res1994 5184187
Not in our library10.1203/00006450-199402000-00012
- 123.
Wahn V Aberer W Eberl W Faßhauer M Kühne T Hereditary angioedema (HAE) in children and adolescents--a consensus on therapeutic strategiesEur J Pediatr2012 513391348
Not in our library10.1007/s00431-012-1726-4
- 124.
Yip J Cunliffe WJ Hormonally exacerbated hereditary angioedemaAustralas J Dermatol1992 53538
Not in our library10.1111/j.1440-0960.1992.tb00050.x
- 125.
Visy B Fust G Varga L Szendei G Takács E Sex hormones in hereditary angioneurotic oedemaClin Endocrinol (Oxf)2004 5508515
Not in our library10.1111/j.1365-2265.2004.02009.x
- 126.
Bouillet L Longhurst H Boccon-Gibod I Bork K Bucher C Disease expression in women with hereditary angioedemaAm J Obstet Gynecol2008 5484e1-e4
Not in our library10.1016/j.ajog.2008.04.034
- 127.
Cox M Holdcroft A Hereditary angioneurotic oedema: current management in pregnancyAnaesthesia1995 5547549
Not in our library10.1111/j.1365-2044.1995.tb06050.x
- 128.
Duvvur S Khan F Powell K Hereditary angioedema and pregnancyJ Matern Fetal Neonatal Med2007 5563565
Not in our library10.1080/14767050701411851
- 129.
Bouillet L Hereditary angioedema in womenAllergy Asthma Clin Immunol2010 517
Not in our library10.1186/1710-1492-6-17
- 130.
Czaller I Visy B Csuka D Füst G Tóth F Farkas H The natural history of hereditary angioedema and the impact of treatment with human C1-inhibitor concentrate during pregnancy: a long-term surveyEur J Obstet Gynecol Reprod Biol2010 54449
Not in our library10.1016/j.ejogrb.2010.05.008
- 131.
Montinaro V Castellano G Management of pregnancy and vaginal delivery by C1 inhibitor concentrate in two hereditary angioedema twinsClin Immunol2010 5456457
Not in our library10.1016/j.clim.2010.05.008
- 132.
Longhurst HJ Carr S Khair K C1-inhibitor concentrate home therapy for hereditary angioedema: a viable, effective treatment optionClin Exp Immunol2007 51117
Not in our library10.1111/j.1365-2249.2006.03256.x
- 133.
Aygoren-Pursun E Martinez-Saguer I Rusicke E Klingebiel T Kreuz W On demand treatment and home therapy of hereditary angioedema in Germany--the Frankfurt experienceAllergy Asthma Clin Immunol2010 521
Not in our library10.1186/1710-1492-6-21
- 134.
Farkas H Csuka D Zotter Z Varga L Böröcz Z Home treatment of hereditary angioedema with icatibant administered by health care professionalsJ Allergy Clin Immunol2012 5851852.e2
Not in our library10.1016/j.jaci.2011.10.039
- 135.
Kreuz W Rusicke E Martinez-Saguer I Aygören-Pürsün E Heller C Klingebiel T Home therapy with intravenous human C1-inhibitor in children and adolescents with hereditary angioedemaTransfusion2012 5100107
Not in our library10.1111/j.1537-2995.2011.03240.x
- 136.
Tourangeau LM Castaldo AJ Davis DK Koziol J Christiansen SC Zuraw BL Safety and efficacy of physician-supervised self-managed c1 inhibitor replacement therapyInt Arch Allergy Immunol2012 5417424
Not in our library10.1159/000329635
- 137.
Wilson DA Bork K Shea EP Rentz AM Blaustein MB Pullman WE Economic costs associated with acute attacks and long-term management of hereditary angioedemaAnn Allergy Asthma Immunol2010 5314320
Not in our library10.1016/j.anai.2010.01.024
- 138.
Zilberberg MD Jacobsen T Tillotson G The burden of hospitalizations and emergency department visits with hereditary angioedema and angioedema in the United States, 2007Allergy Asthma Proc2010 5511519
Not in our library10.2500/aap.2010.31.3403
- 139.
Gorman PJ Hereditary angioedema and pregnancy: a successful outcome using C1 esterase inhibitor concentrateCan Fam Physician2008 5365366
Not in our library
- 140.
Farkas H Fust G Fekete B Karádi I Varga L Eradication of Helicobacter pylori and improvement of hereditary angioneurotic oedemaLancet2001 516951696
Not in our library10.1016/s0140-6736(01)06720-4
- 141.
Bork K Barnstedt SE Laryngeal edema and death from asphyxiation after tooth extraction in four patients with hereditary angioedemaJ Am Dent Assoc2003 510881094
Not in our library10.14219/jada.archive.2003.0323
Cited by papers we hold 7
- The International/Canadian Hereditary Angioedema Guideline · 2019Corrected
- Epidemiology of Bradykinin-mediated angioedema: a systematic investigation of epidemiological studies · 2018No notice
- Outcomes of long term treatments of type I hereditary angioedema in a Turkish family · 2017Not checked
- Expert Perspectives on Hereditary Angioedema: Key Areas for Advancements in Care across the Patient Journey · 2016Not checked
- The influence of trigger factors on hereditary angioedema due to C1-inhibitor deficiency · 2014No notice
- Hereditary angioedema with C1 inhibitor deficiency: delay in diagnosis in Europe · 2013No notice
- Hereditary angioedema: how to approach it at the emergency department?Not checked
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