La vitamine D, une nouvelle panacée ?

Besides its well known anti-rachitic properties, vitamin D has numerous in vitro and in vivo actions on the proliferation-differentiation of epidermal and cancer cells, as well as on the recruitment, differentiation and activities of the immune cells. Even though numerous association studies have suggested a possible link between a low vitamin D status and the risk of developing tumoral, auto-immune, neurologic or cardiovascular diseases, further data have proven to be more discordant and at best modest. In addition, the range of vitamin D doses or status active on these extra-skeletal pathologies remains poorly defined, between insufficiency and overload. Looking forward to clearly needed randomized intervention studies, optimal vitamin D status and intakes remain best defined on the basis of the vitamin D indisputable effects on calcium homeostasis and skeletal mineralization.

Abstract licence: CC BY

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