Improved tag-switch method reveals that thioredoxin acts as depersulfidase and controls the intracellular levels of protein persulfidation

Abstract

H 2 S signals via protein persulfidation. To be regulatory the modification will have to be reversible. Using a new method for persulfide detection, we discover this missing link and show that thioredoxin system acts as depersulfidase in vivo .

Cited by papers we hold 3

• Hydrogen Sulfide Signaling in Plants: Emerging Roles of Protein Persulfidation · 2018
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• H2S-Induced Sulfhydration: Biological Function and Detection Methodology · 2017
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• Persulfidation proteome reveals the regulation of protein function by hydrogen sulfide in diverse biological processes in Arabidopsis · 2017
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