A palmitate-rich metastatic niche enables metastasis growth via p65 acetylation resulting in pro-metastatic NF-κB signaling

References 95

1. 1.

   Bergers G, Fendt SM. The metabolism of cancer cells during metastasis. Nature reviews Cancer. 2021;21:162-180.

   Not in our library10.1038/s41568-020-00320-2

2. 2.

   Martin-Perez M, Urdiroz-Urricelqui U, Bigas C, Benitah SA. The role of lipids in cancer progression and metastasis. Cell metabolism. 2022;34:1675-1699.

   Not in our library10.1016/j.cmet.2022.09.023

3. 3.

   Broadfield LA, Pane AA, Talebi A, Swinnen JV, Fendt SM. Lipid metabolism in cancer: New perspectives and emerging mechanisms. Dev Cell. 2021;56:1363-1393.

   Not in our library10.1016/j.devcel.2021.04.013

4. 4.

   Altea-Manzano P, Cuadros AM, Broadfield LA, Fendt SM. Nutrient metabolism and cancer in the in vivo context: a metabolic game of give and take. EMBO Rep. 2020;21:e50635.

   Not in our library10.15252/embr.202050635

5. 5.

   Peinado H, et al. Pre-metastatic niches: organ-specific homes for metastases. Nature Reviews Cancer. 2017;17:302-317.

   Not in our library10.1038/nrc.2017.6

6. 6.

   Doglioni G, Parik S, Fendt SM. Interactions in the (Pre)metastatic Niche Support Metastasis Formation. Front Oncol. 2019;9:219.

   Not in our library10.3389/fonc.2019.00219

7. 7.

   Fong MY, et al. Breast-cancer-secreted miR-122 reprograms glucose metabolism in premetastatic niche to promote metastasis. Nat Cell Biol. 2015;17:183-194.

   Not in our library10.1038/ncb3094

8. 8.

   Christen S, et al. Breast cancer-derived lung metastasis show increased pyruvate carboxylase-dependent anaplerosis. Cell Reports. 2016;17:837-848.

   Not in our library10.1016/j.celrep.2016.09.042

9. 9.

   Rinaldi G, et al. In Vivo Evidence for Serine Biosynthesis-Defined Sensitivity of Lung Metastasis, but Not of Primary Breast Tumors, to mTORC1 Inhibition. Molecular Cell. 2021;81:386-397.

   Not in our library10.1016/j.molcel.2020.11.027

10. 10.

    Heppner G, Miller F, Malathy Shekhar PV. Nontransgenic models of breast cancer. Breast cancer research: BCR. 2000;2:331-334.

    Not in our library10.1186/bcr77

11. 11.

    Lee E, Pandey NB, Popel AS. Pre-treatment of mice with tumor-conditioned media accelerates metastasis to lymph nodes and lungs: a new spontaneous breast cancer metastasis model. Clinical & experimental metastasis. 2014;31:67-79.

    Not in our library10.1007/s10585-013-9610-9

12. 12.

    Erler JT, et al. Hypoxia-Induced Lysyl Oxidase Is a Critical Mediator of Bone Marrow Cell Recruitment to Form the Premetastatic Niche. Cancer cell. 2009;15:35-44.

    Not in our library10.1016/j.ccr.2008.11.012

13. 13.

    Sceneay J, et al. Primary Tumor Hypoxia Recruits CD11b+/Ly6Cmed/Ly6G+ Immune Suppressor Cells and Compromises NK Cell Cytotoxicity in the Premetastatic Niche. Cancer research. 2012;72:3906.

    Not in our library10.1158/0008-5472.can-11-3873

14. 14.

    Peinado H, et al. Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. Nature medicine. 2012;18:883-891.

    Not in our library10.1038/nm.2753

15. 15.
    Alveolar lipids in pulmonary disease. A review · 2020

    No notice
16. 16.

    Ombrato L, et al. Metastatic-niche labelling reveals parenchymal cells with stem features. Nature. 2019;572:603-608.

    Not in our library10.1038/s41586-019-1487-6

17. 17.
    High fat diet activates adult mouse lung stem cells and accelerates several aging-induced effects · 2018

    Not checked
18. 18.
    Alveolar lipids in pulmonary disease. A review · 2020

    No notice
19. 19.
    Proline metabolism supports metastasis formation and could be inhibited to selectively target metastasizing cancer cells · 2017

    No notice
20. 20.

    Elia I, et al. Breast cancer cells rely on environmental pyruvate to shape the metastatic niche. Nature. 2019;568:117-121.

    Not in our library10.1038/s41586-019-0977-x

21. 21.

    Lien EC, et al. Low glycaemic diets alter lipid metabolism to influence tumour growth. Nature. 2021;599:302-307.

    Not in our library10.1038/s41586-021-04049-2

22. 22.

    Vivas-García Y, et al. Lineage-Restricted Regulation of SCD and Fatty Acid Saturation by MITF Controls Melanoma Phenotypic Plasticity. Mol Cell. 2020;77:120-137.

    Not in our library10.1016/j.molcel.2019.10.014

23. 23.

    Broadfield LA, et al. Fat Induces Glucose Metabolism in Nontransformed Liver Cells and Promotes Liver Tumorigenesis. Cancer research. 2021;81:1988-2001.

    Not in our library10.1158/0008-5472.can-20-1954

24. 24.

    Ciriello G, et al. Comprehensive Molecular Portraits of Invasive Lobular Breast Cancer. Cell. 2015;163:506-519.

    Not in our library10.1016/j.cell.2015.09.033

25. 25.

    Curtis C, et al. The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups. Nature. 2012;486:346-352.

    Not in our library10.1038/nature10983

26. 26.

    Kalucka J, et al. Quiescent Endothelial Cells Upregulate Fatty Acid ß-Oxidation for Vasculoprotection via Redox Homeostasis. Cell metabolism. 2018;28:881-894.

    Not in our library10.1016/j.cmet.2018.07.016

27. 27.

    Campbell SL, Wellen KE. Metabolic Signaling to the Nucleus in Cancer. Molecular Cell. 2018;71:398-408.

    Not in our library10.1016/j.molcel.2018.07.015

28. 28.

    Choudhary C, Weinert BT, Nishida Y, Verdin E, Mann M. The growing landscape of lysine acetylation links metabolism and cell signalling. Nature Reviews Molecular Cell Biology. 2014;15:536-550.

    Not in our library10.1038/nrm3841

29. 29.
    Causal analysis approaches in Ingenuity Pathway Analysis · 2013

    No notice
30. 30.

    Huber MA, et al. NF-kappaB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression. The Journal of clinical investigation. 2004;114:569-581.

    Not in our library10.1172/jci21358

31. 31.

    Pino AM, Rodríguez JP. Is fatty acid composition of human bone marrow significant to bone health? Bone. 2019;118:53-61.

    Not in our library10.1016/j.bone.2017.12.014

32. 32.

    Ferraro GB, et al. Fatty acid synthesis is required for breast cancer brain metastasis. Nature Cancer. 2021;2:414-428.

    Not in our library10.1038/s43018-021-00183-y

33. 33.

    Parik S, et al. GBM tumors are heterogeneous in their fatty acid metabolism and modulating fatty acid metabolism sensitizes cancer cells derived from recurring GBM tumors to temozolomide. Frontiers in Oncology. 2022;12.

    Not in our library10.3389/fonc.2022.988872

34. 34.

    Calao M, Burny A, Quivy V, Dekoninck A, Van Lint C. A pervasive role of histone acetyltransferases and deacetylases in an NF-κB-signaling code. Trends in biochemical sciences. 2008;33:339-349.

    Not in our library10.1016/j.tibs.2008.04.015

35. 35.

    Qin JD, et al. Effect of ammonium pyrrolidine dithiocarbamate (PDTC) on NF-κB activation and CYP2E1 content of rats with immunological liver injury. Pharm Biol. 2014;52:1460-1466.

    Not in our library10.3109/13880209.2014.898075

36. 36.

    Haque ME, et al. The GCN5: its biological functions and therapeutic potentials. Clin Sci (Lond). 2021;135:231-257.

    Not in our library10.1042/cs20200986

37. 37.

    Bondy-Chorney E, Denoncourt A, Sai Y, Downey M. Nonhistone targets of KAT2A and KAT2B implicated in cancer biology (1). Biochem Cell Biol. 2019;97:30-45.

    Not in our library10.1139/bcb-2017-0297

38. 38.

    Stilling RM, et al. K-Lysine acetyltransferase 2a regulates a hippocampal gene expression network linked to memory formation. The EMBO journal. 2014;33:1912-1927.

    Not in our library10.15252/embj.201487870

39. 39.

    Chimenti F, et al. A Novel Histone Acetyltransferase Inhibitor Modulating Gcn5 Network: Cyclopentylidene-[4-(4’-chlorophenyl)thiazol-2-yl)hydrazone. Journal of Medicinal Chemistry. 2009;52:530-536.

    Not in our library10.1021/jm800885d

40. 40.

    Pascual G, et al. Dietary palmitic acid promotes a prometastatic memory via Schwann cells. Nature. 2022.

    Not in our library10.1038/s41586-021-04075-0

Cited by papers we hold 2

• Targeted Lung Premetastasis Niche: Mechanisms, Strategies, and Application · 2025
  Not checked
• Effects of dietary intervention on human diseases: molecular mechanisms and therapeutic potential · 2024
  No notice

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