Human alveolar progenitors generate dual lineage bronchioalveolar organoids
Karen Hoffmann, Benedikt Obermayer, Katja Hönzke and 25 more
Communications Biology · 2022
doi:10.1038/s42003-022-03828-5 (opens in a new tab)
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Abstract
The GSK3 inhibitor CHIR99021 is required to maintain the alveolar lineage in alveolar progenitors grown in airway media or AT2 cells become plastic, with the observed effects acting outside of its role as a GSK3B inhibitor.
Abstract licence: CC BY-NC-ND
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