In-vitro engineered human cerebral tissues mimic pathological circuit disturbances in 3D
Aref Saberi, Albert P. Aldenkamp, Nicholas A. Kurniawan and 1 more
Communications Biology · 2022
doi:10.1038/s42003-022-03203-4 (opens in a new tab)
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Abstract
A method is developed to engineer cerebral tissues with intact 3D neuronal networks, mimicking neuropathological signatures such as the propagation of epileptiform discharges, using a multi-chambered tissue culture chip.
Abstract licence: CC BY-NC-ND
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