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Non-invasive human skin transcriptome analysis using mRNA in skin surface lipids

Takayoshi Inoue, Tetsuya Kuwano, Yuya Uehara and 9 more

Communications Biology · 2022

doi:10.1038/s42003-022-03154-w (opens in a new tab)

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Abstract

Inoue et al develop a non-invasive method of analyzing human skin mRNA using RNA in skin surface lipids collected with oil-blotting films. The authors outline the validation of this methodology and describe an application to determine transcriptome in skin surface lipids in patients with atopic dermatitis versus healthy skin.

Abstract licence: CC BY-NC-ND

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