Fascin1 empowers YAP mechanotransduction and promotes cholangiocarcinoma development
Arianna Pocaterra, Gloria Scattolin, Patrizia Romani and 6 more
Communications Biology · 2021
doi:10.1038/s42003-021-02286-9 (opens in a new tab)
We email you when a new notice or a question about this paper appears.
Abstract
Pocaterra et al. demonstrate that Fascin1 F-actin bundling protein sustains YAP activation in the tumour environment in response to extracellular matrix mechanical cues. This study highlights Fascin1 as a potential clinical target in intrahepatic cholangiocarcinoma development.
Abstract licence: CC BY-NC-ND
Reads
Read by people on this page
None yet.
Checked or read by AI through naulon
None yet.
A person counts once a day per paper. We keep no cookie and no address: a reader is a hash that changes every day. Any month under five reads shows no number.
Are you an author?
Is this your paper?
Claim it to add your note and be paid when agents cite it. Free.