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Will AI become our Co-PI?

Dillan Prasad, Aditya Khandeshi, Spencer Sartin and 5 more

npj Digital Medicine · 2025

doi:10.1038/s41746-025-01859-w (opens in a new tab)

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Abstract

Abstract Rapid advances in large language models (LLMs) are transforming the role of students and principal investigators (PIs) in biomedical research. This perspective examines how LLMs can reshape the laboratory model as de facto “Co-PIs” for tasks ranging from literature triage to hypothesis generation. By clarifying both opportunities and risks, we propose a framework for efficient AI collaboration which aims to guide investigators and trainees in harnessing LLMs responsibly.

Abstract licence: CC BY-NC-ND

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