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Unique pattern of neutrophil migration and function during tumor progression

Sima Patel, Shuyu Fu, Jerome Mastio and 19 more

Nature Immunology · 2018

doi:10.1038/s41590-018-0229-5

References 50

  1. 1.

    Fridlender ZG Polarization of tumor-associated neutrophil phenotype by TGF-beta: “N1” versus “N2” TAN. Cancer Cell 16, 183–194 (2009 ).

    Not in our library10.1016/j.ccr.2009.06.017

  2. 2.

    Eruslanov EB Tumor-associated neutrophils stimulate T cell responses in early-stage human lung cancer. J Clin Invest 124, 5466–5480 (2014 ).

    Not in our library10.1172/jci77053

  3. 3.

    Veglia F, Perego M & Gabrilovich D Myeloid-derived suppressor cells coming of age. Nat Immunol in press (2018 ).

    Not in our library10.1038/s41590-017-0022-x

  4. 4.

    Coffelt SB, Wellenstein MD & de Visser KE Neutrophils in cancer: neutral no more. Nat Rev Cancer 16, 431–446 (2016 ).

    Not in our library10.1038/nrc.2016.52

  5. 5.

    Zhou J, Nefedova Y, Lei A & Gabrilovich D Neutrophils and PMN-MDSC: Their biological role and interaction with stromal cells. Semin Immunol (2017 ).

    Not in our library10.1016/j.smim.2017.12.004

  6. 6.

    Ortiz ML Immature myeloid cells directly contribute to skin tumor development by recruiting IL-17-producing CD4+ T cells. J Exp Med 212, 351–367 (2015 ).

    Not in our library10.1084/jem.20140835

  7. 7.

    Ortiz ML, Lu L, Ramachandran I & Gabrilovich DI Myeloid-derived suppressor cells in the development of lung cancer. Cancer Immunol Res 2, 50–58 (2014 ).

    Not in our library10.1158/2326-6066.cir-13-0129

  8. 8.
  9. 9.

    Seyfried TN & Huysentruyt LC On the origin of cancer metastasis. Critical reviews in oncogenesis 18, 43–73 (2013 ).

    Not in our library10.1615/critrevoncog.v18.i1-2.40

  10. 10.

    Achberger S Circulating immune cell and microRNA in patients with uveal melanoma developing metastatic disease. Mol Immunol 58, 182–186 (2013 ).

    Not in our library10.1016/j.molimm.2013.11.018

  11. 11.

    Weide B Myeloid-derived suppressor cells predict survival of patients with advanced melanoma: comparison with regulatory T cells and NY-ESO-1- or melan-A-specific T cells. Clin Cancer Res 20, 1601–1609 (2014 ).

    Not in our library10.1158/1078-0432.ccr-13-2508

  12. 12.

    Condamine T, Ramachandran I, Youn JI & Gabrilovich DI Regulation of tumor metastasis by myeloid-derived suppressor cells. Annu Rev Med 66, 97–110 (2015 ).

    Not in our library10.1146/annurev-med-051013-052304

  13. 13.

    Coffelt SB IL-17-producing gammadelta T cells and neutrophils conspire to promote breast cancer metastasis. Nature 522, 345–348 (2015 ).

    Not in our library10.1038/nature14282

  14. 14.
  15. 15.

    Liu Y MicroRNA-494 Is Required for the Accumulation and Functions of Tumor-Expanded Myeloid-Derived Suppressor Cells via Targeting of PTEN. The Journal of Immunology 188, 5500–5510 (2012 ).

    Not in our library10.4049/jimmunol.1103505

  16. 16.

    Yang L Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis. Cancer Cell 13, 23–35 (2008 ).

    Not in our library10.1016/j.ccr.2007.12.004

  17. 17.

    Huh SJ, Liang S, Sharma A, Dong C & Robertson GP Transiently entrapped circulating tumor cells interact with neutrophils to facilitate lung metastasis development. Cancer Res 70, 6071–6082 (2010 ).

    Not in our library10.1158/0008-5472.can-09-4442

  18. 18.

    Ichikawa M, Williams R, Wang L, Vogl T & Srikrishna G S100A8/A9 activate key genes and pathways in colon tumor progression. Mol Cancer Res 9, 133–148 (2011 ).

    Not in our library10.1158/1541-7786.mcr-10-0394

  19. 19.

    Kowanetz M Granulocyte-colony stimulating factor promotes lung metastasis through mobilization of Ly6G+Ly6C+ granulocytes. Proc Natl Acad Sci U S A 107, 21248–21255 (2010 ).

    Not in our library10.1073/pnas.1015855107

  20. 20.

    Kolaczkowska E & Kubes P Neutrophil recruitment and function in health and inflammation. Nat Rev Immunol 13, 159–175 (2013 ).

    Not in our library10.1038/nri3399

  21. 21.
  22. 22.

    Kumar V, Patel S, Tcyganov E & Gabrilovich DI The Nature of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment. Trends Immunol (2016 ).

    Not in our library10.1016/j.it.2016.01.004

  23. 23.

    Brandau S Myeloid-derived suppressor cells in the peripheral blood of cancer patients contain a subset of immature neutrophils with impaired migratory properties. J Leukoc Biol 89, 311–317 (2011 ).

    Not in our library10.1189/jlb.0310162

  24. 24.

    Kato M Transgenic mouse model for skin malignant melanoma. Oncogene 17, 1885–1888 (1998 ).

    Not in our library10.1038/sj.onc.1202077

  25. 25.

    Hingorani SR Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice. Cancer Cell 7, 469–483 (2005 ).

    Not in our library10.1016/j.ccr.2005.04.023

  26. 26.

    Greenberg NM Prostate cancer in a transgenic mouse. Proc Natl Acad Sci U S A 92, 3439–3443 (1995 ).

    Not in our library10.1073/pnas.92.8.3439

  27. 27.

    Evans RA Lack of immunoediting in murine pancreatic cancer reversed with neoantigen. JCI insight 1 (2016 ).

    Not in our library10.1172/jci.insight.88328

  28. 28.

    Casbon AJ Invasive breast cancer reprograms early myeloid differentiation in the bone marrow to generate immunosuppressive neutrophils. Proc Natl Acad Sci U S A 112, E566–575 (2015 ).

    Not in our library10.1073/pnas.1424927112

  29. 29.

    Biswas SK Metabolic Reprogramming of Immune Cells in Cancer Progression. Immunity 43, 435–449 (2015 ).

    Not in our library10.1016/j.immuni.2015.09.001

  30. 30.

    Chen Y ATP release guides neutrophil chemotaxis via P2Y2 and A3 receptors. Science 314, 1792–1795 (2006 ).

    Not in our library10.1126/science.1132559

  31. 31.

    Chen Y Purinergic signaling: a fundamental mechanism in neutrophil activation. Sci Signal 3, ra45 (2010 ).

    Not in our library10.1126/scisignal.2000549

  32. 32.

    Junger WG Purinergic regulation of neutrophil chemotaxis. Cell Mol Life Sci 65, 2528–2540 (2008 ).

    Not in our library10.1007/s00018-008-8095-1

  33. 33.

    Junger WG Immune cell regulation by autocrine purinergic signalling. Nature reviews. Immunology 11, 201–212 (2011 ).

    Not in our library10.1038/nri2938

  34. 34.

    Chen Y ATP Release Guides Neutrophil Chemotaxis via P2Y2 and A3 Receptors. Science 314, 1792–1795 (2006 ).

    Not in our library10.1126/science.1132559

  35. 35.

    Lecut C P2X1 Ion Channels Promote Neutrophil Chemotaxis through Rho Kinase Activation. The Journal of Immunology 183, 2801–2809 (2009 ).

    Not in our library10.4049/jimmunol.0804007

  36. 36.

    Hind LE, Vincent WJ & Huttenlocher A Leading from the Back: The Role of the Uropod in Neutrophil Polarization and Migration. Developmental cell 38, 161–169 (2016 ).

    Not in our library10.1016/j.devcel.2016.06.031

  37. 37.

    Yang HW, Collins SR & Meyer T Locally excitable Cdc42 signals steer cells during chemotaxis. Nat Cell Biol 18, 191–201 (2016 ).

    Not in our library10.1038/ncb3292

  38. 38.

    Condamine T Lectin-type oxidized LDL receptor-1 distinguishes population of human polymorphonuclear myeloid-derived suppressor cells in cancer patients. Sci Immunol 1 (2016 ).

    Not in our library10.1126/sciimmunol.aaf8943

  39. 39.

    Condamine T ER stress regulates myeloid-derived suppressor cell fate through TRAIL-R-mediated apoptosis. J Clin Invest 124, 2626–2639 (2014 ).

    Not in our library10.1172/jci74056

  40. 40.

    Tybulewicz VL & Henderson RB Rho family GTPases and their regulators in lymphocytes. Nat Rev Immunol 9, 630–644 (2009 ).

    Not in our library10.1038/nri2606

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