A fungal NRPS-PKS enzyme catalyses the formation of the flavonoid naringenin
Hongjiao Zhang, Zixin Li, Shuang Zhou and 5 more
Nature Communications · 2022
doi:10.1038/s41467-022-34150-7 (opens in a new tab)
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Abstract
Biosynthesis of the flavonoid naringenin in plants and bacteria is commonly catalysed by a type III polyketide synthase (PKS) using one p-coumaroyl-CoA and three malonyl-CoA molecules as substrates. Here, the authors report a fungal non-ribosomal peptide synthetase PKS hybrid FnsA catalysing the formation of naringenin.
Abstract licence: CC BY-NC-ND
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