DNA-delivered antibody cocktail exhibits improved pharmacokinetics and confers prophylactic protection against SARS-CoV-2
Elizabeth M. Parzych, Jianqiu Du, Ali R. Ali and 29 more
Nature Communications · 2022
doi:10.1038/s41467-022-33309-6 (opens in a new tab)
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Abstract
Here, Parzych et al describe the development of a DNA-delivered SARS-CoV-2 mAb cocktail displaying synergistic RBD binding that confers broad neutralizing activity against variants of concern and prophylactic efficacy in multiple small animal models.
Abstract licence: CC BY-NC-ND
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