Acetate reprograms gut microbiota during alcohol consumption
Cameron Martino, Livia S. Zaramela, Bei Gao and 16 more
Nature Communications · 2022
doi:10.1038/s41467-022-31973-2 (opens in a new tab)
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Abstract
Chronic alcohol use is associated with intestinal bacterial overgrowth and dysbiosis, but the contribution of ethanol is unclear. Here, using mouse models, the authors find that ethanol is not directly metabolized by the gut microbiota, and that induced changes are rather a side effect of elevated acetate levels.
Abstract licence: CC BY-NC-ND
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