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Confinement anisotropy drives polar organization of two DNA molecules interacting in a nanoscale cavity

Zezhou Liu, Xavier Capaldi, Lili Zeng and 3 more

Nature Communications · 2022

doi:10.1038/s41467-022-31398-x (opens in a new tab)

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Abstract

A nanofluidic model system is used to explore how polymer interactions between large dsDNA molecules can give rise to self-organizing behavior in compartments with controlled anisotropy. The reported findings may help explain the observed non-uniform distribution of plasmids in E. coli.

Abstract licence: CC BY-NC-ND

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