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New recognition specificity in a plant immune receptor by molecular engineering of its integrated domain

Stella Cesari, Yuxuan Xi, Nathalie Declerck and 8 more

Nature Communications · 2022

doi:10.1038/s41467-022-29196-6 (opens in a new tab)

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Abstract

Plant NLR proteins trigger immune responses upon recognition of pathogen effectors. Here the authors show that the integrated decoy domain of the rice NLR RGA5 can be engineered to trigger immune responses upon binding a non-cognate effector.

Abstract licence: CC BY-NC-ND

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