The histone demethylase Kdm6b regulates subtype diversification of mouse spinal motor neurons during development
Wenxian Wang, Hyeyoung Cho, Jae W. Lee and 1 more
Nature Communications · 2022
doi:10.1038/s41467-022-28636-7 (opens in a new tab)
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Abstract
Neural cell type diversification during development is a complex and highly regulated process. Here, the authors show that the histone H3-lysine 27 demethylase Kdm6b promotes and inhibits the generation of specific motor neuron subtypes during the development of the mouse spinal cord.
Abstract licence: CC BY-NC-ND
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