Design of modular autoproteolytic gene switches responsive to anti-coronavirus drug candidates
Nik Franko, Ana Palma Teixeira, Shuai Xue and 2 more
Nature Communications · 2021
doi:10.1038/s41467-021-27072-3 (opens in a new tab)
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Abstract
SARS-CoV-2 proteases are key targets for anti-viral drug development. Here the authors present modular tunable autoproteolytic gene switches for virus free cell culture screening of inhibitors.
Abstract licence: CC BY-NC-ND
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