Dopamine D2 receptor regulates cortical synaptic pruning in rodents
Ya-Qiang Zhang, Wei-Peng Lin, Li-Ping Huang and 3 more
Nature Communications · 2021
doi:10.1038/s41467-021-26769-9 (opens in a new tab)
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Abstract
Synaptic pruning is important during development and synaptic plasticity. Here, the authors show that the dopamine D2 receptor (Drd2) in the anterior cingulate cortex regulates synaptic pruning, affecting LTD and behaviour in transgenic rats.
Abstract licence: CC BY-NC-ND
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