The cell envelope of Staphylococcus aureus selectively controls the sorting of virulence factors
Xuhui Zheng, Gerben Marsman, Keenan A. Lacey and 4 more
Nature Communications · 2021
doi:10.1038/s41467-021-26517-z (opens in a new tab)
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Abstract
The pathogen Staphylococcus aureus releases several pore-forming toxins, termed leukocidins, that kill immune cells. Here, Zheng et al. show that the retention of a leukocidin on bacterial cells and its release are modulated by lipoteichoic acid and a membrane lipid, which also control the sorting of other surface-associated proteins.
Abstract licence: CC BY-NC-ND
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