Electrophysiological engineering of heart-derived cells with calcium-dependent potassium channels improves cell therapy efficacy for cardioprotection
Patrick Vigneault, Sandrine Parent, Pushpinder Kanda and 3 more
Nature Communications · 2021
doi:10.1038/s41467-021-25180-8 (opens in a new tab)
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Abstract
Strategies to improve the function of damaged hearts with progenitor cells have stalled. Here, the authors show that gene transfer of a calcium-dependent potassium channel enhances the functional properties and ability of explant-derived cells to improve heart function after a heart attack.
Abstract licence: CC BY-NC-ND
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