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SNX19 restricts endolysosome motility through contacts with the endoplasmic reticulum

Amra Saric, Spencer A. Freeman, Chad D. Williamson and 5 more

Nature Communications · 2021

doi:10.1038/s41467-021-24709-1 (opens in a new tab)

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Abstract

Endoplasmic reticulum (ER)-interorganelle membrane contact sites have emerged as key regulators of organelle dynamics. Here, the authors report that the ER-resident protein SNX19 mediates ER-endolysosome membrane contacts to maintain the perinuclear distribution of endolysosomes and restrict their motility.

Abstract licence: CC BY-NC-ND

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