Structure of mammalian Mediator complex reveals Tail module architecture and interaction with a conserved core
Haiyan Zhao, Natalie Young, Jens Kalchschmidt and 4 more
Nature Communications · 2021
doi:10.1038/s41467-021-21601-w (opens in a new tab)
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Abstract
The Mediator complex regulates RNA polymerase II transcription in all eukaryotes. The mammalian Mediator cryo-EM structure reveals the architecture of previously unresolved Tail module and suggests its regulatory role in the complex conformation and interactions.
Abstract licence: CC BY-NC-ND
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