Discovery of fungal surface NADases predominantly present in pathogenic species
Øyvind Strømland, Juha P. Kallio, Annica Pschibul and 10 more
Nature Communications · 2021
doi:10.1038/s41467-021-21307-z (opens in a new tab)
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Abstract
Some bacterial pathogens release NADase enzymes into the host cell that deplete the host’s NAD+ pool, thereby causing rapid cell death. Here, Strømland et al. identify NADases on the surface of fungal spores, and show that the enzymes display unique biochemical and structural properties.
Abstract licence: CC BY-NC-ND
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