microRNA-33 maintains adaptive thermogenesis via enhanced sympathetic nerve activity
Takahiro Horie, Tetsushi Nakao, Yui Miyasaka and 30 more
Nature Communications · 2021
doi:10.1038/s41467-021-21107-5 (opens in a new tab)
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Abstract
Adaptive thermogenesis is regulated by central neuronal circuits. Here, the authors show that microRNA-33 in the brain contributes to the maintenance of brown adipose tissue thermogenesis and whole-body energy balance via enhanced sympathetic nerve tone, and regulating the expression of GABAa receptor subunits.
Abstract licence: CC BY-NC-ND
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