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Sensory input drives rapid homeostatic scaling of the axon initial segment in mouse barrel cortex

Nora Jamann, Dominik Dannehl, Nadja Lehmann and 6 more

Nature Communications · 2021

doi:10.1038/s41467-020-20232-x (opens in a new tab)

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Abstract

The axon initial segment (AIS) is critical for action potential initiation and implicated in the regulation of neuronal excitability. The authors describe bidirectional AIS plasticity in a behaviourally relevant context, revealing that the AIS acts in vivo as a homeostatic regulatory domain.

Abstract licence: CC BY-NC-ND

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