Nkx2-5 defines distinct scaffold and recruitment phases during formation of the murine cardiac Purkinje fiber network
Caroline Choquet, Robert G. Kelly, Lucile Miquerol
Nature Communications · 2020
doi:10.1038/s41467-020-19150-9 (opens in a new tab)
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Abstract
Here, the authors apply genetic fate mapping and temporal clonal analysis to study progenitor recruitment and network morphogenesis of murine cardiac Purkinje fibers. Additionally, they characterize how transcription factor dosage regulates cell fate divergence during distinct phases of this process.
Abstract licence: CC BY-NC-ND
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