A network of RNA-binding proteins controls translation efficiency to activate anaerobic metabolism
J. J. David Ho, Nathan C. Balukoff, Phaedra R. Theodoridis and 4 more
Nature Communications · 2020
doi:10.1038/s41467-020-16504-1 (opens in a new tab)
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Abstract
mRNA translation efficiency is regulated in response to stimuli. Here the authors employ mass spectrometry analysis of ribosome fractions and show that under hypoxia, oxygen-sensitive RNA binding proteins enhance the translation efficiency of glycolysis pathway transcripts.
Abstract licence: CC BY-NC-ND
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