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FAM13A affects body fat distribution and adipocyte function

Mohsen Fathzadeh, Jiehan Li, Abhiram Rao and 22 more

Nature Communications · 2020

doi:10.1038/s41467-020-15291-z (opens in a new tab)

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Abstract

Genetic variants in the FAM13A locus have been associated with anthropometric and glycemic traits. Here, using fine-mapping, in vitro knockdown studies in pre-adipocytes and in vivo knockout in mice, the authors show that FAM13A is involved in regulating fat distribution and metabolic traits.

Abstract licence: CC BY-NC-ND

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